Intravenous Anaesthesia: Barbiturates, Benzodiazepines and Propofol

• Q1.Propofol infusion syndrome all except?

  • AOccurs with infusion of propofol for 48 hours or longer
  • BOccurs in critically ill patients
  • CFeatures are nausea and vomiting
  • DFeatures are cardiomyopathy, hepatomegaly
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• Q2.Pain during injection occurs with all except –

  • APropofol
  • BThiopentone
  • CKetamine
  • DEtomidate
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• Q3.Which of the following used as preanesthetic medication causes longest amnesia?

  • AMidazolam
  • BDiazepam
  • CLorazepam
  • DFlunitrazepam
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• Q4.Which of the following determines the speed of recovery from IV anesthetic agents?

  • ALiver metabolism of drug
  • BProtein binding of drug
  • CRedistribution of the drug from sites in the CNS
  • DPlasma clearance of the drug
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• Q5.True about fospropofol is all except

  • AAqueous phosphorylated prodrug of propofol
  • BMore prolonged recovery profile than propofol
  • CPain at the injection site was not reported with fospropofol
  • DSignificantly more respiratory depression than propofol
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• Q6.Which factor of the following contributes to short duration of anesthetic action of single dose thiopental

  • ARapid biotransformation
  • BRapid accumulation in body fat
  • CHigh lipid solubility
  • DAbility to enter and leave brain tissue very rapidly
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• Q7.I.V. anesthesia is:

  • APropofol
  • BSevoflurane
  • CFlumazenil
  • DNaloxone
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• Q8.For propofol all are true except

  • AHas a rapid recovery rate
  • BUsed for induction & maintenance of anesthesia
  • CCauses vomiting after use
  • DCauses sedation
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• Q9.Which induction anaesthetic agent has antiemetic effect?

  • Aetomidate
  • Bpropofol
  • Cthiopentone
  • Dketamine
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• Q10.All of the following are induction agents except:

  • AThiopental
  • BHalothane
  • CNitrous oxide
  • DPropofol
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Answer key

Q1: C. Features are nausea and vomiting; Q2: C. Ketamine; Q3: C. Lorazepam; Q4: C. Redistribution of the drug from sites in the CNS; Q5: D. Significantly more respiratory depression than propofol; Q6: D. Ability to enter and leave brain tissue very rapidly; Q7: A. Propofol; Q8: C. Causes vomiting after use; Q9: B. propofol; Q10: C. Nitrous oxide.

Other topics in Anaesthesia

• History and Ethics of Anaesthesia
• Preoperative Assessment of the Patient
• Intraoperative CNS and CVS Monitoring
• Respiratory Monitoring During Anaesthesia
• Devices for Airway Management
• Intubation
• Anaesthetic Breathing Circuits
• The Anaesthesia Machine and Workstation
• Basic and Paediatric Life Support (BLS and PALS)
• ACLS
• Ventilators and O2 Delivery Devices
• Depolarising Neuromuscular Blockers
• Non-Depolarising Neuromuscular Blockers
• Inhaled Anaesthetics: Basic Properties, N2O and Halothane
• Inhaled Anaesthetics: Fluorinated and Inert Agents with Therapeutic Gases
• Intravenous Anaesthesia: Etomidate, Ketamine and Day-care Surgery
• Local Anaesthetics: Pharmacology and Properties
• Local Anaesthetics: Individual Agents
• Regional Anaesthesia: Methods and Approaches
• Regional Anaesthesia: Risks and Contraindications
• Peripheral Nerve Blockade
• Anaesthetic Implications of Coexisting Disease
• Anaesthesia in Paediatrics and Obstetrics
• Pain Management: Postoperative, Chronic and Cancer Pain
• Perioperative Anaesthetic Complications