Immune System: Organisation, Function and Response
- Previous year questions on Immune System: Organisation, Function and Response for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Microbiology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 155 live questions in Immune System: Organisation, Function and Response.
- 5 of 155 questions carry a verified exam year: 2017, 2018, 2019.
- Microbiology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Prozone phenomenon is due to:
- AAntigen excess
- BAntibody excess✓ Correct answer
- CExcessive immune complex
- DAcute phase reactants
Q2.Superantigen includes all, Except
- ATSST
- BExfoliative toxin
- CPyrogenic exotoxin
- DCholera toxin✓ Correct answer
Q3.Which prevents apoptosis of Memory B Cells?
- APlatelet derived Growth Factor
- BNerve Growth Factor✓ Correct answer
- CFibroblast Growth Factor
- DIGF
Q4.The serum concentration of which of the following human IgG subclass is maximum ?
- AIgG 1✓ Correct answer
- BIgG 2
- CIgG 3
- DIgG 4
Q5.Classical complement activated by:
- AC1
- BC3 Convertase
- CIgA
- DAg - Ab complex✓ Correct answer
Q6.all the following statements about hybridoma technology are true except :
- Aspecific antibody producing cells are integrated with myeloma cell
- Bmyeloma cells in salvage pathway grows well in HAT medium✓ Correct answer
- Caminopterin, a folate antagonist inhibits denovo pathway
- DHGP ase and thymidylate sytnthtase are required for salvage pathway
Q7.A rabbit is injected for the first time with ova-albumin. The antibodies generated in this response would be of which class?
- AIgG
- BIgM✓ Correct answer
- CIgD
- DIgE
Q8.Cell fusion is an innovative technique of preparing specific antibodies. Techniques to induce the cell-fusion include the following except
- ABy adhering some inactivated viruses to surface membrane
- BBy adding component polyethylene glycol
- CBy mild electric shock
- DBy reducing the viscosity of the membrane✓ Correct answer
Q9.Immunoglobulins present in milk
- AIgM
- BIgA✓ Correct answer
- CIgD
- DIgE
Q10.MHC gene is located in:
- AChromosome 12
- BChromosome 6✓ Correct answer
- CChromosome 7
- DChromosome 8
Answer key
Q1: B. Antibody excess; Q2: D. Cholera toxin; Q3: B. Nerve Growth Factor; Q4: A. IgG 1; Q5: D. Ag - Ab complex; Q6: B. myeloma cells in salvage pathway grows well in HAT medium; Q7: B. IgM; Q8: D. By reducing the viscosity of the membrane; Q9: B. IgA; Q10: B. Chromosome 6.
Other topics in Microbiology
- Principles of General Microbiology
- Cells and Organs of the Immune System
- Hypersensitivity
- Disorders of Immunity
- Streptococci and Enterococci
- Staphylococci
- Corynebacterium, Listeria and Actinomyces
- Clostridium and Bacillus
- Non-Sporing Anaerobes
- Mycobacterium Tuberculosis
- Mycobacteria Other Than Tuberculosis
- Escherichia, Proteus and Klebsiella
- Shigella and Salmonella
- Vibrio and Campylobacterales
- Pseudomonas and Burkholderiales
- Haemophilus
- Yersinia, Brucella, Bartonella and Legionella
- Gram-Negative Cocci
- Rickettsia, Chlamydia and Mycoplasma
- Spirochetes
- Virus Structure and General Properties
- DNA Viruses
- Hepatitis
- HIV
- Myxoviruses and Rhabdoviruses
- Arboviruses and Picornaviruses
- Rubella, Coronaviruses, Prions, Rotavirus, Filovirus, Zika Virus and Nipah Virus
- Superficial and Systemic Fungal Infections
- Opportunistic Fungal Infections
- Principles of Parasitology
- Protozoa: Amoebae, Ciliates and Flagellates
- Protozoa: Sporozoa
- Helminths: Cestodes and Trematodes
- Helminths: Nematodes
- Applied Clinical Microbiology