Congenital Adrenal Hyperplasia and Allied Adrenal Disorders
- Previous year questions on Congenital Adrenal Hyperplasia and Allied Adrenal Disorders for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Paediatrics section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 46 live questions in Congenital Adrenal Hyperplasia and Allied Adrenal Disorders.
- 2 of 46 questions carry a verified exam year: 2019, 2020.
- Paediatrics is worth about 10 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following is caused by congenital A-17 hydroxylase deficiency:
- Ahypercalemia
- BHyperkalemia
- CHermaphroditism
- DHypertension✓ Correct answer
Q2.False statement about 21-Hydroxylase deficiency is
- AMost common cause of congenital adrenal hyperplasia
- BAutosomal recessive
- CFemale pseudohermaphroditism
- DMale pseudohermaphroditism✓ Correct answer
Q3.Which condition is associated with Congenital adrenal hypoplasia?
- AMale pseudohermaphroditism✓ Correct answer
- BFemale pseudohermaphroditism
- CTrue pseudohermaphroditism
- DSequential pseudohermaphroditism
Q4.13 yr old child visit OPD with complains of not attaining menarche with karyotype 46 XX. O/E there is clitoromegaly, which enzyme is likely deficient?
- A17 alpha hydroxylase
- B21 alpha hydroxylase✓ Correct answer
- C11 beta hydroxylase
- D3 beta hydroxysteroid dehydrogenase
Q5.A 13yr old child visits gynaec OPD with complaints of not attaining menarche with karyotype 46XX On examination there is cliteromegaly what enzyme likely to be deficient in the above condition
- A21 alpha hydroxylase✓ Correct answer
- B11 beta hydroxylase
- C17 alpha hydroxylase
- D3 beta hydroxysteroid dehydrogenase
Q6.Congenital adrenal hyperplasia is most likely a result of
- ADefects in adrenal steroidogenic enzymes✓ Correct answer
- BAddison's disease
- CDefects in ACTH secretion
- DDefects in corticosteroid-binding globulin
Q7.An 8–day old breast–fed baby presents with vomiting, poor feeding and loose stools. On examination the heart rate is 190/minute, blood pressure 50/30 mmHg, respiratory rate 72 breaths/minute and capillary refill time of 4 seconds. Investigations show hemoglobin level of 15 g/dl. Na 120 mEq/l, K 6.8 mEq/l, Cl 81 meq/l, bicarbonate 15 mEq/l, urea 30 mg/dl and creatinine 0.6 mg/dl. the most likely diagnosis is –
- ACongenital adrenal hyperplasia✓ Correct answer
- BAcute tubular necrosis
- CCongenital hypertrophic pyloric stenosis
- DGalactosemia
Q8.A 10–month old baby previously normal, suddenly becomes distressed in his crib. The external appearance of genitalia was normal, except hyperpigmentation. Blood glucose showed a level of 30 mg%. What is the most probable diagnosis ?
- A21 hydroxylase deficiency
- BHyperinsulinism
- CFamilial glucocorticoid deficiency✓ Correct answer
- DCushing's syndrome
Q9.A 3 week neonate with ambiguous genitalia presented with Na+ 127 meq/L, K+ 7.2 meq/L with BP 52/24 mm Hg and he was managed with IV fluids. What is the next step of management?
- ASpironolactone
- BHydrocortisone administration✓ Correct answer
- CBroad spectrum antibiotics
- DCalcium gluconate
Q10.A female child with virilization, hypertension with low plasma renin diagnosis is
- A21 alpha hydroxylase deficiency
- B11 beta hydroxylase deficiency✓ Correct answer
- C3 beta hydroxylase deficiency
- DConn's syndrome
Answer key
Q1: D. Hypertension; Q2: D. Male pseudohermaphroditism; Q3: A. Male pseudohermaphroditism; Q4: B. 21 alpha hydroxylase; Q5: A. 21 alpha hydroxylase; Q6: A. Defects in adrenal steroidogenic enzymes; Q7: A. Congenital adrenal hyperplasia; Q8: C. Familial glucocorticoid deficiency; Q9: B. Hydrocortisone administration; Q10: B. 11 beta hydroxylase deficiency.
Other topics in Paediatrics
- Neonatology Basics and Routine Newborn Care
- Disorders of the Newborn
- Neonatal Conditions Requiring Special Care
- Apgar Scoring and Neonatal Resuscitation
- Milestones of Development
- Patterns of Growth and Development
- Infant Nutrition and Breastfeeding
- Protein-Energy Malnutrition
- Fat-Soluble Vitamin Deficiencies
- Water-Soluble Vitamin and Trace Element Deficiencies
- Disorders of Fluid and Electrolyte Balance
- Mendelian and Non-Mendelian Inheritance Disorders
- Chromosomal Abnormalities
- Inborn Errors of Amino Acid Metabolism
- Urea Cycle, Complex Molecule and Carbohydrate Metabolic Disorders
- Poliomyelitis and HIV/AIDS
- Bacterial and Parasitic Infections in Children
- Measles, Mumps, Rubella and Other Viral Illnesses
- Surgical GI Conditions in Children
- Medical GI Conditions in Children
- Paediatric Liver Disorders
- Respiratory Disorders of the Newborn
- Respiratory Disorders in Childhood
- Fetal Circulation
- Acyanotic Congenital Heart Disease
- Cyanotic Congenital Heart Disease
- Nephrology in Children
- Urology in Children
- Disorders of the Paediatric Nervous System
- Thyroid Disorders in Children
- Pituitary Gland Disorders
- Pubertal Disorders
- Paediatric Haemato-oncology
- Childhood Solid Tumours
- Musculoskeletal Disorders in Children
- Rheumatological Disorders in Children
- Paediatric Haematology: Bleeding and Clotting Disorders
- Paediatric Anaemias