Paediatric Liver Disorders

Previous year questions on Paediatric Liver Disorders for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Paediatrics section of the exam.
Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
13 live questions in Paediatric Liver Disorders.
2 of 13 questions carry a verified exam year: 2018, 2019.
Paediatrics is worth about 10 of 300 questions on the exam. See every subject’s weightage.
Question set last updated 28 Aug 2026.

Q1.Most common indication of liver transplantation in children:
- ABiliary atresia
- BWilson's disease
- CHemochromatosis
- DPrimary biliary cirrhosis
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Q2.All of the following are true of Reye's syndrome, except -
- AIt frequently complicates viral infections
- BProthrombin time is prolonged
- CDisease may be precipitated by salicylates
- DDeep jaundice is present
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Q3.MC cause of cholestatic jaundice in newborn is
- AHypoplasia of biliary tract
- BNeonatal hepatitis
- CCholedochal cyst
- DPhysiological
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Q4.A 1-month-old child presented with conjugated bilirubinemia and intrahepatic cholestasis. On Liver biopsy staining with PAS, red colored granules were seen inside the hepatocytes. Probable diagnosis is:
- ACongenital hepatic fibrosis
- BWilson's disease
- CAlpha-1 antitrypsin deficiency
- DHemochromatosis
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Q5.Investigation of choice to rule out biliary atresia in a 2-month-old child is:
- AHepatic scintigraphy
- BERCP
- CUSG
- DCT scan.
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Q6.A 4 yr old girl child suffering from vomiting, cerebral edema and is being treated for viral infection from past 5 days. Liver biopsy in this patient may show
- ACentral haemorrhagic necrosis
- BNon-alcoholic steatohepatitis
- CAutoimmune hepatitis
- DMicrovesicular steatohepatitis
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Q7.A neonate presents with jaundice and clay coloured stools. Liver biopsy shows giant cells diagnosis is –
- ANeonatal hepatitis with physiological jaundice
- BNeonatal hepatitis with extrahepatic biliary atresia
- CPhysiological jaundice
- DPhysiological jaundice with extrahepatic biliary atresia
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Q8.A neonate is being investigated for jaundice. A liver biopsy shows features of a "Giant Cell/Neonatal hepatitis". Which one of the following conditions usually results in this case –
- ACongenital hepatic fibrosis
- BHemochromatosis
- CAlpha–1–antitrypsin deficiency
- DGlycogen storage disease Type 1
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Q9.In a child with active liver failure, the most important prognosis factor for death is –
- AIncreasing transaminases
- BIncreasing bilirubin
- CIncreasing prothrombin time
- DGram (–)ve sepsis
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Q10.A 4-year old girl presents with severe vomiting after a viral fever of 5 days. She is hospitalized and develops cerebral edema. Liver biopsy is most likely to demonstrate which of the following?
- ACentrizonal hemorrhagic necrosis
- BNon-alcoholic steatohepatitis
- CRing granulomas
- DMarked microvesicular steatosis
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Answer key

Q1: A. Biliary atresia; Q2: D. Deep jaundice is present; Q3: B. Neonatal hepatitis; Q4: C. Alpha-1 antitrypsin deficiency; Q5: A. Hepatic scintigraphy; Q6: D. Microvesicular steatohepatitis; Q7: B. Neonatal hepatitis with extrahepatic biliary atresia; Q8: C. Alpha–1–antitrypsin deficiency; Q9: C. Increasing prothrombin time; Q10: D. Marked microvesicular steatosis.

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Paediatric Liver Disorders

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