Calcium and Phosphate Regulation
- Previous year questions on Calcium and Phosphate Regulation for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Physiology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 41 live questions in Calcium and Phosphate Regulation.
- 1 of 41 questions carries a verified exam year: 2018.
- Physiology is worth about 17 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following suppress the activity of osteoblasts?
- AVitamin D3
- BT3 and T4
- CCorticosterone✓ Correct answer
- DParathormone
Q2.True about Calcitonin are all except
- AInhibit osteoclast mediated bone resorption
- BIncreases phosphate excretion in kidneys
- CUseful in treating acute hypercalcemic crisis
- DPlays a major role in the regulation of calcium levels in humans✓ Correct answer
Q3.Which of the following hormones regulates blood levels of 1,25-OH-cholecalciferol positively:
- AThyroxine
- BParathormone✓ Correct answer
- CInsulin
- DCalcitonin
Q4.Biomineralization is a process by which inorganic `metals' are incorporated in the body and made a pa of biological structures. Example of Biomineralization is seen in:
- APinna (anatomy)
- BHooves of cattle
- CHoneycomb
- DMollusc shell✓ Correct answer
Q5.Enzymes, which play an important role in calcification, are:
- AEnolase and Calcitonin
- BAlkaline phosphatase and catalase
- CAlkaline phosphatase and pyrophosphatase✓ Correct answer
- DPyrophosphatase and carbonic anhydrase
Q6.Which of the following is associated with a low concentration of ionized calcium in the serum?
- AHypothyroidism
- BOsteogenesis imperfecta
- CPaget's disease of the bone
- DTetany✓ Correct answer
Q7.The decreased phosphate levels seen in hyper parathyroidism is due to:
- ADecreased intestinal phosphate absorption
- BIncreased calcium excretion
- CDecreased renal phosphate absorption✓ Correct answer
- DIncreased loss of phosphate in urine
Q8.Which of the following statements is not true?
- AParathyroid hormone-related protein is responsible for causing hypercalcemia in cancer patients
- BThe unionized fraction of calcium in the plasma is an important determinant of PTH secretion✓ Correct answer
- CMg2+ influences PTH secretion in the same direction as Ca2+ but is a less potent secretagogue
- DCa2+influences PTH secretion by acting on a calcium sensor G-protein coupled receptor located in the parathyroid gland
Q9.Osteoclasts have all of the following except -
- ABone resorption
- BReceptor for parathormone✓ Correct answer
- CRuffled border
- DRank ligand
Q10.The most significant immediate result of lowered serum calcium is
- AWeakened heart action
- BDecalcification of bones
- CDecalcification of teeth
- DHyperirritability of nerves and muscles✓ Correct answer
Answer key
Q1: C. Corticosterone; Q2: D. Plays a major role in the regulation of calcium levels in humans; Q3: B. Parathormone; Q4: D. Mollusc shell; Q5: C. Alkaline phosphatase and pyrophosphatase; Q6: D. Tetany; Q7: C. Decreased renal phosphate absorption; Q8: B. The unionized fraction of calcium in the plasma is an important determinant of PTH secretion; Q9: B. Receptor for parathormone; Q10: D. Hyperirritability of nerves and muscles.
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