Receptors and Intracellular Signalling
- Previous year questions on Receptors and Intracellular Signalling for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Physiology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 12 live questions in Receptors and Intracellular Signalling.
- 4 of 12 questions carry a verified exam year: 2018, 2019, 2020.
- Physiology is worth about 17 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 19 Aug 2026.
Q1.IGF-1 acts through which of the following receptors?
- ACytokine related receptor
- BG protein couple receptor
- CTyrosine kinase receptor✓ Correct answer
- DNuclear or cytoplasmic
Q2.The second messengers cyclic AMP and cyclic GMP
- AActivate the same signal transduction pathways
- BAre generated by the activation of cyclases✓ Correct answer
- CActivate the same protein kinase
- DAre important only in sensory transduction
Q3.Phospholipid associated with mechanism of hormone action is
- APhosphatidyl choline
- BPhosphatidyl lecithin
- CPlasmalogen
- DPhosphatidyl inositol✓ Correct answer
Q4.Many signaling pathways involve the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). These molecules
- AAre first messengers
- BActivate phospholipase C
- CAre derived from PIP2✓ Correct answer
- DCan't activate calcium calmodulin-dependent protein kinases directly or indirectly
Q5.Which of the following binds to the Tyrosine kinase receptor?
- ALH
- BInsulin✓ Correct answer
- CTSH
- DTRH
Q6.Which of the following binds to Tyrosine Kinase receptor?
- ALH
- BInsulin✓ Correct answer
- CTSH
- DTRH
Q7.All are true about nitric oxide, EXCEPT:
- ARegulates vasomotor tone
- BActs via cAMP✓ Correct answer
- CPresent in cigarette smoke
- DIt is important in penile erection
Q8.Which hormone act by crossing cell membrane -
- AThyroxine✓ Correct answer
- BInsulin
- CGlucagon
- DCalcitonin
Q9.Second messenger for smooth muscle relaxation mediated by NO is:
- ACa'
- BcAMP
- CcGMP✓ Correct answer
- DMagnesium
Q10.Which of the following has intracellular receptor -
- AGlucagon
- BInsulin
- CEpinephrine
- DThyroxine✓ Correct answer
Answer key
Q1: C. Tyrosine kinase receptor; Q2: B. Are generated by the activation of cyclases; Q3: D. Phosphatidyl inositol; Q4: C. Are derived from PIP2; Q5: B. Insulin; Q6: B. Insulin; Q7: B. Acts via cAMP; Q8: A. Thyroxine; Q9: C. cGMP; Q10: D. Thyroxine.
Other topics in Physiology
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- Membrane Transport Mechanisms
- Resting and Action Membrane Potentials
- Body Fluid Compartments
- Blood Composition, Hemostasis and Blood Groups
- Nerve Conduction and Excitability
- Skeletal Muscle: Structure and Excitation-Contraction Coupling
- Smooth and Cardiac Muscle Mechanics
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- Neurotransmitters
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- Ascending Somatosensory Tracts
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- Motor Control: Spinal Reflexes and Lower Motor Neurons
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- Autonomic Nervous System
- Functional Anatomy of the Airways
- Mechanics of Breathing
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- Spirometry and Lung Volumes
- Respiratory Adaptation to Hypoxia, Anemia and Pressure Extremes
- Control of Ventilation
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- Regional Circulations: Coronary, Cerebral and Splanchnic
- The Cardiac Cycle and Determinants of Output
- Cardiac Electrophysiology and the ECG
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- Male Reproductive Function
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