Resting and Action Membrane Potentials
- Previous year questions on Resting and Action Membrane Potentials for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Physiology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 10 live questions in Resting and Action Membrane Potentials.
- 3 of 10 questions carry a verified exam year: 2017, 2018.
- Physiology is worth about 17 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 19 Aug 2026.
Q1.Delivery of stimulus above threshold intensity leads to a constant amplitude of AP and is known as:
- AAll or none law✓ Correct answer
- BElectronic potential
- CAbsolute refractory period
- DRelative refractory period
Q2.The electrical potential difference necessary for a single ion to be at equilibrium across a membrane is best described by the
- AGoldman equation
- BVan't Hoff equation
- CFick's law
- DNernst equation✓ Correct answer
Q3.Resting membrane potential of nerve fibre is close to isoelectric potential of:
- APotassium ions✓ Correct answer
- BSodium ions
- CChloride ions
- DMagnesium ions
Q4.At equilibrium the concentrations of Cl- inside and outside a cell are 8 mmol/L and 120 mmol/L, respectively. The equilibrium potential for Cl- at 37oC is calculated to be
- A+4.07 mV
- B-4.07 mV
- C+71.7 mV
- D-71.7 mV✓ Correct answer
Q5.Resting membrane potential is determined by
- ANa+
- BK+✓ Correct answer
- CCI-
- DMg++
Q6.Cell membrane of a cell is freely permeable to three ions X, Y and Z. At resting membrane potential, the respective equilibrium potentials of Xand Y are -30mV and -40 mV.What will happen to the membrane potential if a drug is infused which can block the permeability of Z?
- ADepolarisation✓ Correct answer
- BHyperpolarization
- CNo change
- DHyperpolarization following repolarization
Q7.Absolute refractoriness of a neuron is due to?
- AClosure of activated Na channels
- BClosure of inactivated Na channels✓ Correct answer
- CHyperpolarization of CI channels
- DOpening of rectifier K + channels
Q8.In excitable cells, repolarization is closely associated with one of the following events:
- ANa+ efflux
- BNa+ influx
- CK+ efflux✓ Correct answer
- DK+ influx
Q9.Potential generated due to movement of freely diffusible ions across a semi-permeable membrane is calculated using:
- ANernst equation✓ Correct answer
- BGibbs equation
- CGoldman-Hodgkin-Katz equation
- DFick principle
Q10.The concentration of a negative ion is 100 mmol/L extracellular and 10 mmol/L intracellular. What will be the Nernst potential for this ion?
- A-10 mV
- B+10 mV
- C-61 mV✓ Correct answer
- D+61 mV
Answer key
Q1: A. All or none law; Q2: D. Nernst equation; Q3: A. Potassium ions; Q4: D. -71.7 mV; Q5: B. K+; Q6: A. Depolarisation; Q7: B. Closure of inactivated Na channels; Q8: C. K+ efflux; Q9: A. Nernst equation; Q10: C. -61 mV.
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