DNA Packaging, Replication and Repair
- Previous year questions on DNA Packaging, Replication and Repair for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Biochemistry section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 108 live questions in DNA Packaging, Replication and Repair.
- 10 of 108 questions carry a verified exam year: 2017, 2018, 2019, 2020.
- Biochemistry is worth about 16 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Melting temperature of DNA is:-
- AProportional to AT pairs
- BProportional to GC pairs✓ Correct answer
- CNo relation with base pair composition
- DDirectly proportional to length of DNA
Q2."Proofreading" is the role of
- ADNA primase
- BDNA Polymerase✓ Correct answer
- CExonuclease I
- DRestriction endonuclease
Q3.Which of the following is the etiology of Werner syndrome?
- AIncreased length of telomere
- BShort telomere with damaged DNA and loss of helicase✓ Correct answer
- CIncreased advanced glycation end products
- DDecreased lipid peroxidation
Q4.The type mutation that leads to replacement of valine for glutamate in sickle cell disease is?
- APoint mutation✓ Correct answer
- BSilent mutation
- CNonsense mutation
Q5.Telomerase has action of:
- ADNA polymerase 1
- BDNA polymerase 2
- CDNA polymerase 3
- DReverse transcriptase✓ Correct answer
Q6.True regarding mitochondrial DNA is:
- ALinear double stranded
- BInherited from mother✓ Correct answer
- CLow mutation rate
- DAll respiratory proteins are synthesized within mitochondria itself
Q7.True statement regarding base excision repair is ?
- AUsed only for the bases which are deaminated
- BUses enzyme called as DNA glycosylase which generate abasic suger site✓ Correct answer
- CRemoves about 10 – 15 nucleotide
- DRecognizes a bulk lesion
Q8.The bases which are present in human DNA?
- AAdenine-guanine-thiamine- uracil
- BAdenine-guanine- cytosine-uracil
- CAdenine- guanine-cytosine-thymine✓ Correct answer
- DNone of the above
Q9.True about telomerase is:
- ARibonucleoprotein✓ Correct answer
- BTranscriptional factor activation
- CMembrane receptor
- DDNA binding domain
Q10.removing RNA primer from both leading and lagging strand by ?
- ADNA POLYMERASE 1✓ Correct answer
- BDNA POLYMERASE 2
- CDNA POLYMERASE 3
- DDNA LIGASE
Answer key
Q1: B. Proportional to GC pairs; Q2: B. DNA Polymerase; Q3: B. Short telomere with damaged DNA and loss of helicase; Q4: A. Point mutation; Q5: D. Reverse transcriptase; Q6: B. Inherited from mother; Q7: B. Uses enzyme called as DNA glycosylase which generate abasic suger site; Q8: C. Adenine- guanine-cytosine-thymine; Q9: A. Ribonucleoprotein; Q10: A. DNA POLYMERASE 1.
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- Bioenergetics and the ETC
- Krebs Cycle
- Amino Acids: Structure and Classification
- Amino Acid Metabolism and Nitrogen Handling
- Inborn Errors of Amino Acid Metabolism
- Levels of Protein Structure and Function
- Urea Cycle and Hyperammonaemia
- Lipids: Classification and Chemistry
- Beta-Oxidation and Ketone Body Formation
- Fatty Acid Synthesis and Eicosanoids
- Acylglycerol and Sphingolipid Metabolism
- Cholesterol Metabolism and Lipoprotein Transport
- Haem Synthesis, Porphyrias and Bile Pigments
- Enzymes: Mechanism of Action and Clinical Uses
- Enzyme Kinetics, Inhibition and Regulation
- Fat-Soluble Vitamins: A, D, E and K
- B-Complex Vitamins in Energy Metabolism
- Folate, Vitamin B12 and Other Vitamins
- Minerals and Antioxidant Systems
- Nucleotide Metabolism and Its Disorders
- Transcription and RNA Processing
- Translation and Post-Translational Modification
- Control of Gene Expression
- Recombinant DNA and Genomic Techniques