Nucleotide Metabolism and Its Disorders
- Previous year questions on Nucleotide Metabolism and Its Disorders for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Biochemistry section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 7 live questions in Nucleotide Metabolism and Its Disorders.
- 2 of 7 questions carry a verified exam year: 2018, 2019.
- Biochemistry is worth about 16 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 19 Aug 2026.
Q1.Azaserine inhibits
- AGlycinamide ribonucleotide synthetase
- BGlycinamide ribonucleotide transformylase
- CFormyl glycinamide ribonucleotide amidotransferase✓ Correct answer
- DInosine monophosphate synthase
Q2.Allantoin is the end product of metabolism of ?
- AGlycogen
- BPurine✓ Correct answer
- CPyrimidine
- DHistidine
Q3.The enzyme deficient in Lysch Nyhan syndrome is:-
- AAdenosine Deaminase
- BPRPP synthetase
- CHGPase✓ Correct answer
- DXanthine oxidase
Q4.What is involved in formation of d-TMP from d- UMP?
- AN5, N10-methylene tetrahydrofolate✓ Correct answer
- BFormimino folate
- CN5 formyl folate
- DDihydrofolate
Q5.Which is a product of purine metabolism?
- AUric acid✓ Correct answer
- BUrea
- CXanthine
- DBeta alanine
Q6.First purine nucleotide, which is synthesized in purine biosynthesis ?
- AAMP
- BGMP
- CIMP✓ Correct answer
- DUMP
Q7.A child presented at 2 years of age with delayed motor development, mental retardation and finger biting. He was normal at birth. He subsequently develops cerebral palsy arthritis and dies due to renal failure at age of 25 years. What is the likely enzyme deficiency implicated?
- AHexosaminidase deficiency
- BAdenosine deaminase deficiency
- CHGP deficiency✓ Correct answer
- DOrnithine transcarbamoylase deficiency
Answer key
Q1: C. Formyl glycinamide ribonucleotide amidotransferase; Q2: B. Purine; Q3: C. HGPase; Q4: A. N5, N10-methylene tetrahydrofolate; Q5: A. Uric acid; Q6: C. IMP; Q7: C. HGP deficiency.
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- Amino Acids: Structure and Classification
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- Enzymes: Mechanism of Action and Clinical Uses
- Enzyme Kinetics, Inhibition and Regulation
- Fat-Soluble Vitamins: A, D, E and K
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- Folate, Vitamin B12 and Other Vitamins
- Minerals and Antioxidant Systems
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- Transcription and RNA Processing
- Translation and Post-Translational Modification
- Control of Gene Expression
- Recombinant DNA and Genomic Techniques