Urea Cycle and Hyperammonaemia
- Previous year questions on Urea Cycle and Hyperammonaemia for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Biochemistry section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 12 live questions in Urea Cycle and Hyperammonaemia.
- 5 of 12 questions carry a verified exam year: 2018, 2019.
- Biochemistry is worth about 16 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 3 Sept 2026.
Q1.Ammonia is detoxified in brain by:
- ACreatinine
- BUric acid
- CGlutamine✓ Correct answer
- DUrea
Q2.Ammonia formed in brain, is converted into
- AGlutamine✓ Correct answer
- BGlycine
- CCysteine
- DUrea
Q3.Ammonia causes depletion of which of the following in TCA cycle?
- AOxaloacetate
- BAlpha-Keto glutarate✓ Correct answer
- CFumarate
- DMalate
Q4.Which of the following amino acid in a protein is involved in urea cycle and is required for synthesis of Nitric Oxide?
- AArginine✓ Correct answer
- BHistidine
- CTryptophan
- DLysine
Q5.Which one of the following can be converted to an intermediate of either the citric acid cycle or the urea cycle?
- ATyrosine
- BLysine
- CLeucine
- DAspartate✓ Correct answer
Q6.Amino acid linking Kreb's cycle & urea cycle:-
- AAspartate✓ Correct answer
- BFumarate
- CAlanine
- DArginine
Q7.Glutamine is increased in CSF, blood & urine in which defect:
- AArginosuccinate synthetase
- BOTC
- CCPS-I✓ Correct answer
- DArginase
Q8.The amino acid that acts as a precursor in the production of urea is
- AArginine✓ Correct answer
- BAspartic acid
- COrnithine
- DGlutamate
Q9.Drugs used in urea cycle disorders to reduce ammonia?
- APhenyl butarone
- BPhenyl butyrate✓ Correct answer
- CL - Carnitine
- DIsoleucin
Q10.Ammonia from brain is removed as:
- AUrea
- BAlanine
- CGlutamate
- DGlutamine✓ Correct answer
Answer key
Q1: C. Glutamine; Q2: A. Glutamine; Q3: B. Alpha-Keto glutarate; Q4: A. Arginine; Q5: D. Aspartate; Q6: A. Aspartate; Q7: C. CPS-I; Q8: A. Arginine; Q9: B. Phenyl butyrate; Q10: D. Glutamine.
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