Enzyme Kinetics, Inhibition and Regulation
- Previous year questions on Enzyme Kinetics, Inhibition and Regulation for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Biochemistry section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 15 live questions in Enzyme Kinetics, Inhibition and Regulation.
- 2 of 15 questions carry a verified exam year: 2018, 2020.
- Biochemistry is worth about 16 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 19 Aug 2026.
Q1.Allosteric enzymes show the following characteristics, except
- ACo-operative binding of substrate
- BObey Sigmoid saturation kinetics
- CEffector site overlap with the active site✓ Correct answer
- DActive site and effector site need not be located on the same subunit
Q2.Competitive inhibition is characterized by all the following, except
- AInhibitor is a structural analogue of the substrate
- BInhibitor binds to the active site
- CIncreases Km value
- DIrreversible✓ Correct answer
Q3.Non-competitive Inhibitors
- AIncrease Km
- BDecrease Km
- CIncrease Vmax
- DDecrease Vmax✓ Correct answer
Q4.Inhibition of placental Alkaline Phosphatase by Phenylalanine is an example of
- ACompetitive Inhibition
- BNoncompetitive inhibition
- CUncompetitive Inhibition✓ Correct answer
- DAllosteric Inhibition
Q5.TRUE ABOUT NON - COMPETITIVE INHIBITION IS ?
- AKm remains same ,Vmax decrease✓ Correct answer
- BKm increase , Vmax increase
- CKm decrease , Vmax increase
- DKm increase, Vmax increases
Q6.All the following is characteristic of uncompetitive inhibition except
- AInhibitor is not a substrate analogue
- BInhibitor binds to the active site✓ Correct answer
- CInhibitor binds to the ES complex
- DVmax and Km decreased
Q7.Which of the following is a competitive inhibitor of Succinate Dehydrogenase enzyme?
- ASuccinic acid
- BFumaric acid
- CMalonic acid✓ Correct answer
- DOxalic acid
Q8.Non competitive inhibition has
- ADecreased km and decreased Vmax
- BNORMAL km and decreased Vmax✓ Correct answer
- CDecreased km and increased Vmax
- Dnormal km and increased Vmax
Q9.All are examples of competitive enzyme blockage except
- ACyclooxygenase by Aspirin✓ Correct answer
- BThymidylate synthase by 5-FU
- CCoagulation by Dicumarol
- DDHFR by Methotrexate
Q10.Km increases, but Vmax remains same. This is.... Inhibition:
- ACompetitive✓ Correct answer
- BNon-competitive
- CIrreversible
- DUncompetitive
Answer key
Q1: C. Effector site overlap with the active site; Q2: D. Irreversible; Q3: D. Decrease Vmax; Q4: C. Uncompetitive Inhibition; Q5: A. Km remains same ,Vmax decrease; Q6: B. Inhibitor binds to the active site; Q7: C. Malonic acid; Q8: B. NORMAL km and decreased Vmax; Q9: A. Cyclooxygenase by Aspirin; Q10: A. Competitive.
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