Antiepileptics: Newer and Broad-Spectrum Agents
- Previous year questions on Antiepileptics: Newer and Broad-Spectrum Agents for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 15 live questions in Antiepileptics: Newer and Broad-Spectrum Agents.
- 1 of 15 questions carries a verified exam year: 2019.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.True about Levetiracetam is
- AMost useful in Prophylaxis of migraine
- BPoor oral absorption
- CLinear kinetics✓ Correct answer
- DExtensively metabolized by Cytochrome P450
Q2.Cannabinoids are approved by USFDA in June 2018 for new use of
- AEpilepsy✓ Correct answer
- BUTI
- CTB
- DChicken pox
Q3.Which of the following is granted orphan drug status for the treatment of Dravet’s syndrome?
- AStiripentol✓ Correct answer
- BIcatibant
- CPitolisant
- DTafamidis
Q4.Least teratogenic antiepileptic drug in pregnancy is;
- AValproate
- BPhenytoin
- CCarbamazepine
- DLevetiracetam✓ Correct answer
Q5.Which of these anticonvulsants causes contraction of visual field?
- ALevetiracetam
- BPhenytoin
- CVigabatrin✓ Correct answer
- DEthosuximide
Q6.Recently approved drug by FDA for treatment of Lennox-Gestaut syndrome:
- ALacosamide
- BVigabatrin
- CZonisamide
- DRufinamide✓ Correct answer
Q7.Patient is a known case of epilepsy, taking levetiracetam 1 gm BD. He is now seizure free from 2 years but he developed agitation and anger issues interfering with day to day activities as a result of the drug intake. What should be the next best step?
- AStop levetiracetam and start on a different antiepileptic
- BDiscontinue the drug as he is seizure free
- CSlowly taper the drug over next 6 months✓ Correct answer
- DContinue levetiracetam since a 5-year seizure free interval is needed
Q8.Anti-epileptic which is not associated with congenital malformation when used in pregnant woman is:
- APhenytoin
- BPhenobarbitone✓ Correct answer
- CCarbamazepine
- DValproate
Q9.What is the drug of choice for GTCS in pregnancy?
- ALamotrigine
- BCBZ
- CLevetiracetam✓ Correct answer
- DValproate
Q10.Visual field monitoring is important before starting?
- AVigabatrin✓ Correct answer
- BTopiramate
- CValproic acid
- DCarbamazepine
Answer key
Q1: C. Linear kinetics; Q2: A. Epilepsy; Q3: A. Stiripentol; Q4: D. Levetiracetam; Q5: C. Vigabatrin; Q6: D. Rufinamide; Q7: C. Slowly taper the drug over next 6 months; Q8: B. Phenobarbitone; Q9: C. Levetiracetam; Q10: A. Vigabatrin.
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