Pharmacokinetics: Applied Calculations
- Previous year questions on Pharmacokinetics: Applied Calculations for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 10 live questions in Pharmacokinetics: Applied Calculations.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.A 80 kg patient is brought in casualty. Patient is in shock. Vasopressor is to be started at 10 microgram/kg/min. Vial has 200 mg in 5 ml, 2 vials diluted in 250 ml NS. 16 drops is equal to 1 ml. Calculate drops per minute required
- A8✓ Correct answer
- B16
- C24
- D32
Q2.A drug X was given continuous intravenous infusion at 1.6 mg/min. The clearance of the drug is 640 mL/min. With a half-life of 1.8 hours, what would be the steady state plasma concentration of drug?
- A0.002 mg/mL✓ Correct answer
- B0.004 mg/mL
- C2.88 mg/mL
- D3.55 mg/mL
Q3.A patient requires 180 mg ceftriaxone. The vial contains 500 mg/5ml of ceftriaxone. You have a 2 ml syringe with 10 divisions per ml. How many divisions in the 2 ml syringe will you fill to give 180 mg ceftriaxone?
- A9
- B18✓ Correct answer
- C10
- D12
Q4.An 80 kg male patient presented to the emergency with hypotension and you have been instructed to start him on an inotrope at a dose of 10 mcg/kg/min. Each 5 mL amp of the drug contains 200 mg drug. You choose 2 ampules of the drug and decide to mix it with saline to make a 250 mL solution. What should be the flow rate of the drug solution to maintain the BP of the patient (assuming 16 drops = 1 mL)?
- A4 drops/min
- B8 drops/min✓ Correct answer
- C10 drops/min
- D16 drops/min
Q5.A patient is administered 200 mg of a drug. 75 mg of the drug is eliminated from the body in 90 minutes. If the drug follows first order kinetics, how much drug will remain after 6 hours?
- A12.5 mg
- B25 mg
- C30 mg✓ Correct answer
- D50 mg
Q6.A patient requires ceftriaxone 180 mg. You have a 2 mL syringe with 10 divisions per mL. The vial contains 500 mg/5 mL of ceftriaxone. How many divisions in the 2 mL syringe will you fill to give 180 mg ceftriaxone?
- A18✓ Correct answer
- B1.8
- C20
- D2
Q7.Concentration of a drug in blood is 40 microgram/ml. Dose of the drug is 200mg. Volume of distribution of the drug assuming minute elimination is ?
- A5 litre✓ Correct answer
- B0.5 litre
- C2.5 litre
- D3 litre
Q8.Drug A, has Bioavailability of 80% volume of distribution is 10 L, Calculate the loading dose to be given to achieve plasma concentration of 0.6 mg/L
- A0.75 mg
- B0.48 mg
- C7.5 mg✓ Correct answer
- D48 mg
Q9.Drug X is normally administered to patients at a rate of 50 mg/hour. Elimination of the drug X from body takes place as: - Hepatic Metabolism 10% - Biliary Secretion 10% - Renal Excretion 80% This drug has to be administered to a 65 years old patient Uttaam Singh, with a GFR of 60 ml/min. (assuming normal GFR is 120ml/min). Liver and biliary functions are normal in this patient. What should be the dose rate of drug X in this patient?
- A50 mg/hour
- B30 mg/hr✓ Correct answer
- C25 mg/hr
- D100 mg/hr.
Q10.A patient was given a 160 mg dose of a drug IV, and 80 mg was eliminated during the first 120 minutes. If the drug follows first-order elimination kinetics, how much of the drug will remain 6 hours after its administration?
- A10 mg
- B20 mg✓ Correct answer
- C40 mg
Answer key
Q1: A. 8; Q2: A. 0.002 mg/mL; Q3: B. 18; Q4: B. 8 drops/min; Q5: C. 30 mg; Q6: A. 18; Q7: A. 5 litre; Q8: C. 7.5 mg; Q9: B. 30 mg/hr; Q10: B. 20 mg.
Other topics in Pharmacology
- Pharmacokinetics
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- Semisynthetic and Synthetic Opioid Analgesics
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- Antifungals
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- NSAIDs
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- DMARDs for Rheumatoid Arthritis
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