Antiepileptics: Sodium Channel and GABAergic Agents
- Previous year questions on Antiepileptics: Sodium Channel and GABAergic Agents for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 33 live questions in Antiepileptics: Sodium Channel and GABAergic Agents.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.which anti epileptic on long term use causes PSEUDOLYMPHOMA ?
- Aphenytoin✓ Correct answer
- Bphenobarbitones
- Cvalproate
- Dcarbamizapine
Q2.Adverse effects of phenytoin include all of the following except?
- ALymphadenopathy
- BAtaxia
- CHypercalcemia✓ Correct answer
- DHirsutism
Q3.Which of the following factors markedly increases the risk of valproate-induced liver toxicity?
- AMale gender
- BAge younger than 2 year✓ Correct answer
- CFamily history of epilepsy
- DAllergic reactions to phenobarbital
Q4.Carbamazepine has been utilized to successfully diminish attacks in trigeminal neuralgia. During this therapy, which of the following is indicated?
- AClinical observation only
- BClinical observation and complete blood and platelet counts prior to and at frequent intervals during therapy✓ Correct answer
- CNo monitoring
- DComplete blood investigation, only if adverse symptoms arise
Q5.Idiosyncratic side-effects of carbamazepine are all except:
- ASteven-Johnson syndrome
- BAgranulocytosis
- CRash
- DBlurred vision✓ Correct answer
Q6.Which of the following is true about carbamazepine?
- ANot associated with agranulocytosis
- BHas been known to cause Steven-Johnson's syndrome✓ Correct answer
- CCauses serious nephrogenic toxicity
- DDrug monitoring is not required
Q7.Which of the following drugs is least efficacious in the treatment of temporal lobe epilepsy?
- APhenobarbitone
- BPhenytoin sodium
- CPrimidone✓ Correct answer
- DCarbamazepine
Q8.Which one of the following is a gender-specific side-effect of valproate?
- APolycystic ovarian syndrome✓ Correct answer
- BAlopecia
- CWeight loss
- DTremor
Q9.For which of the following seizures would Carbamazepine be prescribed as the appropriate drug treatment for prevention?
- AGeneralized tonic clonic
- BSimple partial
- Cstatus epilepticus
- DComplex partial✓ Correct answer
Q10.Drug avoided in patient with non-ketotic hyperglycemia with seizure is -
- ACarbamazepine
- BValproate
- CPhenytoin✓ Correct answer
- DClobazam
Answer key
Q1: A. phenytoin; Q2: C. Hypercalcemia; Q3: B. Age younger than 2 year; Q4: B. Clinical observation and complete blood and platelet counts prior to and at frequent intervals during therapy; Q5: D. Blurred vision; Q6: B. Has been known to cause Steven-Johnson's syndrome; Q7: C. Primidone; Q8: A. Polycystic ovarian syndrome; Q9: D. Complex partial; Q10: C. Phenytoin.
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