Antihistamines
- Previous year questions on Antihistamines for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 20 live questions in Antihistamines.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.The following drug inhibits histamine release
- AD tubocurare
- BMorphine
- CSuxamethonium
- DKetotifin✓ Correct answer
Q2.ICATIBANT IS A ?
- Abradykinin B 1 antagonist
- Bbradykinin B 2 antagonist✓ Correct answer
- Cbradykinin B 3 antagonist
- Dhistamine receptor H3 antagonist
Q3.Vasodilatation is caused by:
- ASerotonin
- BHistamine✓ Correct answer
- CLT C4
- DThromboxane A2
Q4.Your medical student patient suffers from troublesome allergic rhinitis due to pollen, and you want to prescribe a drug for her that is least likely to cause sedation. Your best choice would be
- Abetamethasone
- Bcimetidine
- Chydroxyzine
- Dloratadine✓ Correct answer
Q5.Fexofenadine is metabolic product of
- ALoratidine
- BAstemizole
- CCetrizine
- DTerfenadine✓ Correct answer
Q6.Prodrug of cetrizine is -
- AFexofenadine
- BTerfenadine
- CHydroxyzine✓ Correct answer
- DAzelastine
Q7.Which of the following can reverse one or more smooth muscle effects of circulating histamine in humans?
- AGranisetron
- BAdrenaline✓ Correct answer
- CRanitidine
- DSumatriptan
Q8.Ketotifen is a:
- ALeucotriene antagonist
- BAntibody against IgE
- CMast cell stabilizer✓ Correct answer
- DMucolytic & expectorant
Q9.All of the following actions of histamine are mediated through H1 receptors EXCEPT:
- ARelease of EDRF from vascular endothelium resulting in vasodilation
- BDirect action on vascular smooth muscle causing vasodilation✓ Correct answer
- CBronchoconstriction
- DRelease of catecholamines from adrenal medulla
Q10.Olopatadine is:
- AMast cell stabilizer
- BAnti-histamine
- CBoth mast cell stabilizer and anti histamine✓ Correct answer
- DNone of the above
Answer key
Q1: D. Ketotifin; Q2: B. bradykinin B 2 antagonist; Q3: B. Histamine; Q4: D. loratadine; Q5: D. Terfenadine; Q6: C. Hydroxyzine; Q7: B. Adrenaline; Q8: C. Mast cell stabilizer; Q9: B. Direct action on vascular smooth muscle causing vasodilation; Q10: C. Both mast cell stabilizer and anti histamine.
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