Semisynthetic and Synthetic Opioid Analgesics
- Previous year questions on Semisynthetic and Synthetic Opioid Analgesics for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 30 live questions in Semisynthetic and Synthetic Opioid Analgesics.
- 1 of 30 questions carries a verified exam year: 2017.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following feature differentiates pethidine from morphine?
- ALocal anaesthetic action✓ Correct answer
- BMore analgesic action
- CMore respiratory depression
- DSuppresses cough effectively
Q2.The shoest acting opioid is:-
- AFentanyl
- BSulfentanil
- CRemifentanil✓ Correct answer
- DAlfentanyl
Q3.A 50-year-old man is brought to the emergency department by ambulance. His respirations are shallow and infrequent, his pupils are constricted, and he is stuporous. He was noted to have suffered a grand mal seizure in the ambulance. Which drug is this man likely to have overdosed on?
- ACocaine
- BLSD
- CMeperidine✓ Correct answer
- DPCP
Q4.Shortest acting synthetic opioid is
- AFentanyl
- BRemifentanil✓ Correct answer
- CAlfentanil
- DSufentanil
Q5.Pethidine is pharmacologically different from morphine because it
- ACauses more sedation
- BCauses more constipation
- CHas additional Anticholinergic action✓ Correct answer
- DCauses spasm of sphincter of Oddi
Q6.Heroin, an addict drug contains
- AASA
- BAcetyl morphine✓ Correct answer
- CPentazocine
- DPropoxyphene
Q7.Like all opioids, tramadol acts as an analgesic drug by stimulating mu opioid receptors. Apart from this, the additional mechanism of action of tramadol is?
- ASerotonin and nor-adrenaline reuptake inhibition✓ Correct answer
- BAnticholinergic
- CAntihistaminic
- DSerotonin and dopamine reuptake inhibition
Q8.Chest wall rigidity can be caused by rapid infusion of which of the following opioid-
- AFentanyl
- BSufentanyl
- CRemifentanil
- DAll of the above✓ Correct answer
Q9.Muscle rigidity is caused by which anaesthetic
- AHalothane
- BEther
- CSevoflurane
- DAlfentanil✓ Correct answer
Q10.Muscle Rigidity is caused by which agent
- AFentanyl✓ Correct answer
- BHalothane
- CKetamine
- DDroperidol
Answer key
Q1: A. Local anaesthetic action; Q2: C. Remifentanil; Q3: C. Meperidine; Q4: B. Remifentanil; Q5: C. Has additional Anticholinergic action; Q6: B. Acetyl morphine; Q7: A. Serotonin and nor-adrenaline reuptake inhibition; Q8: D. All of the above; Q9: D. Alfentanil; Q10: A. Fentanyl.
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- Pharmacodynamics
- Adverse Drug Reactions and Pharmacovigilance
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- Sympathomimetics
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- Antianginal Agents
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- Antiparkinsonian Drugs
- Antidepressants and Anxiolytics
- Opioids: Classification and Actions
- Opioid Receptor Antagonists
- Ethanol and Other Alcohols
- Drugs for Alzheimer's and Neurodegenerative Disease
- Principles of Antimicrobial Use and Resistance
- Antimalarials
- Folate Antagonists, Quinolones and Urinary Antiseptics
- Drugs Targeting the 30S Ribosomal Subunit
- Drugs Targeting the 50S Ribosomal Subunit
- Antiretroviral Therapy for HIV
- Penicillins
- Cephalosporins, Carbapenems and Glycopeptides
- Other Antibacterial Agents
- Antiprotozoals and Anthelmintics
- Antifungals
- First-Line Antitubercular Drugs
- Second-Line and MDR-TB Regimens
- Antileprotic Drugs
- Antivirals: Non-Retroviral Agents
- Hypothalamic and Pituitary Hormones
- Thyroid Hormones and Antithyroid Drugs
- Corticosteroids
- Drugs for Osteoporosis and Calcium Disorders
- Antidiabetics: Oral Agents
- Antidiabetics: Insulins and Injectables
- Estrogens, Progestins and OCPs
- Androgens and Erectile Dysfunction Therapy
- Uterine Stimulants and Relaxants
- NSAIDs
- Drugs for Migraine and Gout
- DMARDs for Rheumatoid Arthritis
- Immunosuppressants and Immunomodulators
- Antihistamines
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