Antiparkinsonian Drugs
- Previous year questions on Antiparkinsonian Drugs for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 15 live questions in Antiparkinsonian Drugs.
- 2 of 15 questions carry a verified exam year: 2017, 2018.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.The selective MAO-B inhibitor among the following is
- ASelegiline✓ Correct answer
- BClorgyline
- CMoclobemide
- DTranylcypromine
Q2.Tetrabenazine acts by inhibiting
- AMAO-B
- BVesicular monoamine transporter✓ Correct answer
- CDopamine D2 receptors
- DCOMT
Q3.Antiparkinsonian drug activating D2 receptors directly
- APramipexole✓ Correct answer
- BEntacapone
- CBenserazide
- DSelegiline
Q4.The use of levodopa is avoided in which of the following patients?
- AAlzheimer's disease
- BPsychosis✓ Correct answer
- CMultiple sclerosis
- DAmyotrophic lateral sclerosis
Q5.Entacapone acts by inhibiting which of the following enzyme?
- ACOMT✓ Correct answer
- BMAO-A
- CMAO-B
- DDecarboxylase
Q6.Entacapone may be useful in patients being treated with levodopa-carbidopa combination because it :
- AActivates COMT
- BDecreases formation of 3–OMD✓ Correct answer
- CInhibits monoamine oxidase type B
- DInhibits dopamine uptake
Q7.Which of the following anti-Parkinson drugs has the potential to cause retro peritoneal fibrosis:
- APramipexole
- BEntacapone
- CBromocriptine✓ Correct answer
- DRopinirole
Q8.Which of the following statements is FALSE regarding drugs in the treatment of Parkinsonism?
- AAmantadine causes ankle edema
- BLevodopa is effective in reducing tremors
- CAmantadine is more effective than levodopa✓ Correct answer
- DAnti-muscarinic agents are effective in drug induced Parkinsonism
Q9.DOC for Levodopa induced vomiting is?
- AMetoclopramide
- BOndansetron
- CDoxylamine
- DDomperidone✓ Correct answer
Q10.Anti–Parkinsonism drug that is a selective COMT inhibitor :
- AEntacapone✓ Correct answer
- BRopinirole
- CPergolide
- DPramipexole
Answer key
Q1: A. Selegiline; Q2: B. Vesicular monoamine transporter; Q3: A. Pramipexole; Q4: B. Psychosis; Q5: A. COMT; Q6: B. Decreases formation of 3–OMD; Q7: C. Bromocriptine; Q8: C. Amantadine is more effective than levodopa; Q9: D. Domperidone; Q10: A. Entacapone.
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