DMARDs for Rheumatoid Arthritis
- Previous year questions on DMARDs for Rheumatoid Arthritis for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 24 live questions in DMARDs for Rheumatoid Arthritis.
- 5 of 24 questions carry a verified exam year: 2017, 2018, 2020.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.60 yr old lady with RA is considered for infliximab therapy tests to be done are
- ALFT
- BPPD skin test✓ Correct answer
- CPFT
- DVisual exam
Q2.Which of the following statement is false about drugs used in rheumatoid arthritis?
- ATofacitinib inhibits JAK1 and JAK3
- BTocilizumab inhibits IL-6
- CTofactinib is given intravenously✓ Correct answer
- DTocilizumab is given by intravenous and subcutaneous route
Q3.Baricitinib was approved by FDA recently for
- AOsteoarthritis
- BRheumatoid arthritis✓ Correct answer
- CC. difficile
- DGout
Q4.Which of the following statement is false regarding Leflunomide:
- AUsed in treatment of Rheumatoid arthritis
- BAct by inhibiting IMP dehydrogenase enzyme✓ Correct answer
- CInhibits proliferation of T and B cells
- DIt is contraindicated in pregnancy
Q5.Newer monoclonal antibody approved for rheumatoid arthritis is:
- ADurvalumab
- BPembrolizumab
- CNivolumab
- DSarilumab✓ Correct answer
Q6.A 45 year old male, known case of Rheumatoid arthritis is on a monotherapy since many years. Symptoms of RA are controlled but suddenly patient develops blurring of vision. Which of the following drug is responsible for sudden affect on vision?
- ALeflunomide
- BMethotrexate
- CSulfasalazine
- DHydroxychloroquine✓ Correct answer
Q7.Which of the following disease modifying anti-rheumatoid drugs acts by increasing extracellular adenosine?
- ALeflunomide
- BHydroxychloroquine
- CAzathioprine
- DMethotrexate✓ Correct answer
Q8.Etanercept is a disease-modifying drug used in management of rheumatoid arthritis. What is its mechanism of action?
- AInhibition of TNF alpha✓ Correct answer
- BCOX-2 inhibition
- CIL-6 inhibition
- DStabilization of mast cells
Q9.Which of the following drugs is not used in management of rheumatoid arthritis?
- AEtanercept
- BLeflunomide
- CFebuxostat✓ Correct answer
- DMethotrexate
Q10.Etanercept used in rheumatoid arthritis act by the inhibition of:
- ATNF alpha✓ Correct answer
- BTGF beta
- CIL-2
- DIL-6
Answer key
Q1: B. PPD skin test; Q2: C. Tofactinib is given intravenously; Q3: B. Rheumatoid arthritis; Q4: B. Act by inhibiting IMP dehydrogenase enzyme; Q5: D. Sarilumab; Q6: D. Hydroxychloroquine; Q7: D. Methotrexate; Q8: A. Inhibition of TNF alpha; Q9: C. Febuxostat; Q10: A. TNF alpha.
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