Penicillins
- Previous year questions on Penicillins for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 28 live questions in Penicillins.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.MECHANISM OF RESISTANCE TO PENICILLIN BETA LACTAMASE IS :
- AALTERED PENICILLIN BINDING PROTEINS
- BDRUG EFFLUX
- CBREAKS DRUG STRUCTURE✓ Correct answer
- DALTERATION IN 50S RIBOSOME STRUCTURE
Q2.The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is:
- AAmpicillin
- BErythromycin
- CPenicillin G✓ Correct answer
- DMethicillin sodium
Q3.Which one of the following is penicillinase resistant penicillin:
- AAmoxycillin
- BCloxacillin✓ Correct answer
- CAmpicillin
- DPenicillin G
Q4.Clavulanic acid added to ampicillin causes:
- AIncrease effectivity against gram-negative organisms
- BInhibition of β-lactamases✓ Correct answer
- CIncreases the effectiveness against delta lactamase producing organism
- DIncrease effectivity against gram-positive organisms
Q5.Not true about piperacilline is:
- AActive against pseudomonas aeruginosa
- BInhibits Beta-lactamase✓ Correct answer
- CIt is a ureido penicillin
- DGiven parenterally
Q6.The most common side effect of the oral administration of ampicillin is
- AAnaphylactic shock
- BDiarrhoea✓ Correct answer
- COral candidiasis
- DRenal failure
Q7.Which antibiotic is effective against pseudomonas and indole +ve proteus?
- AMethicillin
- BCarbenicillin✓ Correct answer
- CLincomycin
- DOxacillin
Q8.Oral infection by penicillinase producing organisms should be treated with:
- AAmpicillin
- BDicloxacillin✓ Correct answer
- CErythromycin
- DAny of the above
Q9.Probenecid interacts with ?
- AStreptomycin
- BAmpicillin✓ Correct answer
- CVancomycin
- DErythromycin
Q10.Jarisch-Herxheimer reaction is seen in syphilis with:
- ATetracyclines
- BPenicillins✓ Correct answer
- CCo-trimoxazole
- DSulfonamides
Answer key
Q1: C. BREAKS DRUG STRUCTURE; Q2: C. Penicillin G; Q3: B. Cloxacillin; Q4: B. Inhibition of β-lactamases; Q5: B. Inhibits Beta-lactamase; Q6: B. Diarrhoea; Q7: B. Carbenicillin; Q8: B. Dicloxacillin; Q9: B. Ampicillin; Q10: B. Penicillins.
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