Drugs Targeting the 30S Ribosomal Subunit
- Previous year questions on Drugs Targeting the 30S Ribosomal Subunit for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 25 live questions in Drugs Targeting the 30S Ribosomal Subunit.
- 4 of 25 questions carry a verified exam year: 2017, 2018, 2019.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.All are false about tigecycline, except:
- ADose reduction in renal failure
- B90% pseudomonas strains are sensitive
- COral and parenteral bioavailability is same
- DNot preferred in UTI✓ Correct answer
Q2.Which of the following aminoglycoside is most cochleotoxic:-
- AAmikacin✓ Correct answer
- BStreptomycin
- CGentamycin
- DMinocycline
Q3.Drug which lacks intrinsic activity against anaerobes is:-
- AAminoglycosides✓ Correct answer
- BBeta lactams
- CChloramphenicol
- DMetronidazole
Q4.An ototoxic drug which mainly affects vestibular component is
- AGentamicin✓ Correct answer
- BAmikacin
- CNetilmicin
- DKanamycin
Q5.Mechanism of resistance of tetracyclines is due to?
- ADrug efflux mechanism✓ Correct answer
- BDevelopment of inactivating enzymes
- CDNA methylation
- DCell wall alteration
Q6.Ototoxic drug which mainly affects vestibular component is
- AGentamicin✓ Correct answer
- BAmikacin
- CNetilmicin
- DKanamycin
Q7.Prolonged administration of streptomycin may result in damage to the:
- AOptic nerve
- BFacial nerve
- CAuditory nerve✓ Correct answer
- DTrigeminal nerve
Q8.Mechanism of action of chlortetracycline:
- AInterfere with metabolism
- BInhibition of protein synthesis✓ Correct answer
- CInhibition of cell wall formation
- DInterfere with DNA function
Q9.Which one of the following antibiotics chelates with calcium ?
- APenicillin
- BTetracycline✓ Correct answer
- CCephalosporins
- DErythromycin
Q10.Gentamicin is not given orally because:-
- AIt has adverse effects on gastric mucosa
- BIt interferes with absorption of other drugs
- CIt is rapidly destroyed by gastric acid
- DIt has poor absorption✓ Correct answer
Answer key
Q1: D. Not preferred in UTI; Q2: A. Amikacin; Q3: A. Aminoglycosides; Q4: A. Gentamicin; Q5: A. Drug efflux mechanism; Q6: A. Gentamicin; Q7: C. Auditory nerve; Q8: B. Inhibition of protein synthesis; Q9: B. Tetracycline; Q10: D. It has poor absorption.
Other topics in Pharmacology
- Pharmacokinetics
- Pharmacodynamics
- Adverse Drug Reactions and Pharmacovigilance
- Clinical Trials and Drug Development
- Pharmacokinetics: Applied Calculations
- ANS Overview and Cholinergic Agonists
- Sympathomimetics
- Parasympatholytics
- Sympatholytics
- Antiglaucoma Agents
- Antianginal Agents
- Drugs for Cardiac Failure
- Antihypertensives
- Diuretics
- Antiarrhythmic Agents
- Lipid-Lowering Agents
- Drugs Acting on the RAAS
- Antidiuretic Agents
- Sedative-Hypnotics
- Antiepileptics: Sodium Channel and GABAergic Agents
- Antiepileptics: Newer and Broad-Spectrum Agents
- Antipsychotic Agents
- Drugs for Mania and Mood Stabilization
- Antiparkinsonian Drugs
- Antidepressants and Anxiolytics
- Opioids: Classification and Actions
- Semisynthetic and Synthetic Opioid Analgesics
- Opioid Receptor Antagonists
- Ethanol and Other Alcohols
- Drugs for Alzheimer's and Neurodegenerative Disease
- Principles of Antimicrobial Use and Resistance
- Antimalarials
- Folate Antagonists, Quinolones and Urinary Antiseptics
- Drugs Targeting the 50S Ribosomal Subunit
- Antiretroviral Therapy for HIV
- Penicillins
- Cephalosporins, Carbapenems and Glycopeptides
- Other Antibacterial Agents
- Antiprotozoals and Anthelmintics
- Antifungals
- First-Line Antitubercular Drugs
- Second-Line and MDR-TB Regimens
- Antileprotic Drugs
- Antivirals: Non-Retroviral Agents
- Hypothalamic and Pituitary Hormones
- Thyroid Hormones and Antithyroid Drugs
- Corticosteroids
- Drugs for Osteoporosis and Calcium Disorders
- Antidiabetics: Oral Agents
- Antidiabetics: Insulins and Injectables
- Estrogens, Progestins and OCPs
- Androgens and Erectile Dysfunction Therapy
- Uterine Stimulants and Relaxants
- NSAIDs
- Drugs for Migraine and Gout
- DMARDs for Rheumatoid Arthritis
- Immunosuppressants and Immunomodulators
- Antihistamines
- Antiplatelet, Fibrinolytic and Antifibrinolytic Agents
- Hematinics
- Anticoagulants
- Drugs for Asthma and COPD
- Drugs for Peptic Ulcer and IBD
- Antiemetics, Prokinetics and Laxatives
- Cell Cycle-Specific Chemotherapy
- Cell Cycle-Nonspecific Chemotherapy
- Monoclonal Antibody Therapeutics
- Cytokines, Growth Factors and Targeted Agents