Immunosuppressants and Immunomodulators
- Previous year questions on Immunosuppressants and Immunomodulators for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pharmacology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 28 live questions in Immunosuppressants and Immunomodulators.
- 3 of 28 questions carry a verified exam year: 2017, 2018, 2019.
- Pharmacology is worth about 20 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.The following is not an immunomodulator
- ATacrolimus
- BCyclosporin
- CCylcoserin✓ Correct answer
- DSirolimus
Q2.All of the following are known adverse effects of thalidomide, except:
- ADiarrhoea✓ Correct answer
- BTeratogenicity
- CDVT
- DNeuropathy
Q3.All of the following immunosuppressives cause profound myelosuppression except:
- ASirolimus
- BCyclosporine✓ Correct answer
- CAzathioprine
- DMercaptopurine
Q4.The adverse effects of thalidomide include following except
- ADiarrhea✓ Correct answer
- BHypothyroidism
- CDeep Venous Thrombosis
- DNeutropenia
Q5.The mechanism of action of cyclosporine is:
- AInhibits IL-2 receptors
- BInhibits TNF alpha
- CDecrease in transcription of IL-2 gene✓ Correct answer
- DTargets inactivated T cells
Q6.Half-life of basiliximab is:-
- A7 days✓ Correct answer
- B7 hours
- C15 days
- D24 hours
Q7.Lenalidomide co-administration with which another drug increases the risk of thrombosis?
- AAlcohol
- BBarbiturates
- CGlucocorticoids✓ Correct answer
- DAntibiotics
Q8.All are adverse effects of cyclosporin, EXCEPT:
- AHypeension
- BGingival hyperplasia
- CHyperlipidemia
- DHypermagnesemia✓ Correct answer
Q9.Which of the following immunosuppressants is not used for the treatment of cancers ?
- ACyclophosphamide
- BCyclosporine✓ Correct answer
- CMethotrexate
- D6–Mercaptopurine
Q10.Which of the following immunosuppressant drugs is nephrotoxic?
- AAzathioprine
- BCyclophosphamide
- CMycophenolate mofetil
- DTacrolimus✓ Correct answer
Answer key
Q1: C. Cylcoserin; Q2: A. Diarrhoea; Q3: B. Cyclosporine; Q4: A. Diarrhea; Q5: C. Decrease in transcription of IL-2 gene; Q6: A. 7 days; Q7: C. Glucocorticoids; Q8: D. Hypermagnesemia; Q9: B. Cyclosporine; Q10: D. Tacrolimus.
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