Crystal-Induced Arthritis
- Previous year questions on Crystal-Induced Arthritis for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 18 live questions in Crystal-Induced Arthritis.
- 3 of 18 questions carry a verified exam year: 2017, 2019.
- Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.The diagnosis of gout is best established by the presence of
- ASynovial uric acid crystals
- BIntracellular uric acid crystals✓ Correct answer
- CElevated serum uric acid
- DInvolvement of the first metatarsal phalangeal joint
Q2.Which type of gout is seen in a patient who is on treatment of CML?
- ASecondary gout✓ Correct answer
- BPseudogout
- CAcute gout
- DPrimary gout
Q3.All of the following are true about Gout, except:-
- AOccurs due to accumulation of urate crystals in joint
- BCan be pptd by pyrazinamide
- CBirefringement crystals are present in joint
- DOccurs more in females✓ Correct answer
Q4.Which of the following is the best investigation for acute gout?
- ASerum uric acid
- BUric acid in synovial fluid✓ Correct answer
- CUric acid in urine
- DAnti CCP antibodies
Q5.Needle shaped crystals negatively birefringent on polarized microscopy is characteristic of which crystal associated arthropathy?
- AGout✓ Correct answer
- BPseudo gout
- CNeuropathic arthropathy
- DHemophilic arthropathy
Q6.Diagnosis of Gout is confirmed by which test?
- ASerum Uric acid level
- BSynovial fluid analysis✓ Correct answer
- CUrine uric acid levels
- DX- ray changes
Q7.A person has severe pain & swelling in great toe.True statements are -a) Allopurinol used in acute control of goutb) Colchicine acts slowlyc) Colchicine cause gastrointestinal disturbancesd) High serum uric acid level may be not presente) Joint fluid aspiration is done for investigation
- Aabd
- Bacd
- Cbde
- Dcde✓ Correct answer
Q8.In a patient with gouty arthritis, synovial fluid aspiration will show -
- AMonosodium Urate crystals✓ Correct answer
- BCalcium Pyrophosphate crystals
- CMononuclear Leucocytosis
- DPolymorphonuclear Leukocytosis
Q9.A 65-year-old man develops the onset of severe right knee pain over 24 hours. The knee is red, swollen, and tender. The patient does not have fever or systemic symptoms; he has never had severe joint pain before. Plain film of the knee shows linear calcification of the articular cartilage without destructive change. Definitive diagnosis is best made by which of the following?
- ASerum uric acid
- BSerum calcium
- CArthrocentesis and identification of positively birefringent rhomboid crystals✓ Correct answer
- DRheumatoid factor
Q10.Most specific diagnostic finding in gout is -
- AUric acid crystals in urine
- BRaised serum uric acid
- CPresence of calcium pyrophosphate crystals in synovial fluid
- DPresence of monosodium crystals in synovial fluid✓ Correct answer
Answer key
Q1: B. Intracellular uric acid crystals; Q2: A. Secondary gout; Q3: D. Occurs more in females; Q4: B. Uric acid in synovial fluid; Q5: A. Gout; Q6: B. Synovial fluid analysis; Q7: D. cde; Q8: A. Monosodium Urate crystals; Q9: C. Arthrocentesis and identification of positively birefringent rhomboid crystals; Q10: D. Presence of monosodium crystals in synovial fluid.
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