Sjogren Syndrome and Scleroderma
- Previous year questions on Sjogren Syndrome and Scleroderma for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 27 live questions in Sjogren Syndrome and Scleroderma.
- 2 of 27 questions carry a verified exam year: 2018.
- Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Most common lymphoma associated with Sicca syndrome is
- ADLBCL
- BMALToma✓ Correct answer
- CBurkitt lymphoma
- DLymphoplasmacytic lymphoma
Q2.A 14 year old girl on exposure to cold has pallor of extremities followed by pain and cyanosis. In later stages of life she is most prone to develop:
- ASLE
- BScleroderma✓ Correct answer
- CRheumatoid Arthritis
- DDermatomyositis
Q3.A patient of scleroderma who has hypertension is at significant risk of developing
- AMI
- BSudden renal failure✓ Correct answer
- CThrombotic stroke
- DPulmonary hypertension
Q4.Anti-alpha fodrin autoantibodies are seen in
- APolymyositis
- BCrohn's disease
- CSjogren's syndrome✓ Correct answer
- DGrave's disease
Q5.In a 30 years old female patient with polyarthritis, testing reveals nucleolar pattern of ANA staining. What is the likely course of this patient?
- AMalar rash, alopecia and renal failure
- BSclerodactyly, esophageal dysmotility and Raynaud's phenomenon✓ Correct answer
- CSjogren's syndrome
- DPainful genital and oral blisters and ulcers
Q6.Anti-centromere antibodies are seen in which of the following conditions?
- ADrug-induced lupus
- BSLE
- CSjogren syndrome
- DScleroderma✓ Correct answer
Q7.Which of the following is not true about the salivary gland output in Sjogren's syndrome?
- AIncrease in sodium concentration
- BIncrease in phosphate concentration✓ Correct answer
- CDecreased output of salivary glands <0.5 ml/min
- DIncrease in IgA concentration
Q8.Anti-centromere antibodies seen in which of the followings conditions:
- ADrug induced lupus
- BSLE
- CSjogren syndrome
- DScleroderma✓ Correct answer
Q9.Female presents with history of color change from pallor to cyanosis on exposure to cold in fingers. This condition is mostly associated with?
- AScleroderma✓ Correct answer
- BLeukemia
- CLung infections
- DHepatosplenomegaly
Q10.Which of the following is false about scleroderma?
- ADigital ulceration
- BGastroesophageal Reflux Disease (GERD)
- CMask like facies
- DFemale preponderance of 9 :1✓ Correct answer
Answer key
Q1: B. MALToma; Q2: B. Scleroderma; Q3: B. Sudden renal failure; Q4: C. Sjogren's syndrome; Q5: B. Sclerodactyly, esophageal dysmotility and Raynaud's phenomenon; Q6: D. Scleroderma; Q7: B. Increase in phosphate concentration; Q8: D. Scleroderma; Q9: A. Scleroderma; Q10: D. Female preponderance of 9 :1.
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