Syndrome of Inappropriate ADH Secretion (SIADH)
- Previous year questions on Syndrome of Inappropriate ADH Secretion (SIADH) for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 9 live questions in Syndrome of Inappropriate ADH Secretion (SIADH).
- 2 of 9 questions carry a verified exam year: 2017, 2018.
- Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Syndrome of inappropriate ADH secretion is characterized by of the following EXCEPT:-
- AHypo-osmolar urine✓ Correct answer
- BWater intoxication
- CExpanded fluid volume
- DHyponatremia
Q2.Cerebral salt wasting occurs due to which of the following?
- ASIADH
- BHyper secretion of ANP✓ Correct answer
- CLow cortisol secretion
- DLow aldosterone secretion
Q3.Which of the following leads to development of SIADH?
- AHead trauma✓ Correct answer
- BPituitary adenoma
- CLithium
- DAll of the above
Q4.Which of the following rightly describes the mechanism of "Pressor Escape" in SIADH?
- ACharacterized by sudden increase in urine volume with decrease in urine osmolality independent of circulating vasopressin levels.✓ Correct answer
- BCharacterized by sudden increase in urine volume with decrease in urine osmolality dependent of circulating vasopressin levels.
- CCharacterized by sudden decrease in urine volume with increase in urine osmolality independent of circulating vasopressin levels.
- DCharacterized by sudden decrease in urine volume with increase in urine osmolality dependent of circulating vasopressin levels.
Q5.A 50 years old smoker and hypertensive was diagnosed to have non-small cell lung carcinoma with brain metastases. He is on enalapril and hydrochlorothiazide for hypertension. On investigation, he had a serum Sodium 120 mg/dl, Urinary Sodium 110 mg/dl, Serum creatinine 0.8 mg/dL, Serum osmolarity 285 mOsm/L, Urinary osmolarity 351 mOsm/L, Urinary K+ 9 mg/dl, Blood sugar 112 mg/dL and BP of 150/90 mm Hg. Which of the following is the most probable cause for his hyponatremia?
- ACerebral salt wasting
- BDiuretic induced
- CSIADH✓ Correct answer
- DPseudohyponatremia
Q6.Dilutional hyponatremia is a side effect of the following except-
- AOctreotide
- BVincristine
- CMannitol✓ Correct answer
- DCarbamazepine
Q7.Dilutional hyponatremia is seen in ?
- AAddison's disease
- BVincristine✓ Correct answer
- CDiuretic therapy
- DCraniphyrangioma
Q8.The syndrome of inappropriate antidiuretic hormone is characterized by the following-
- AHyponatremia and urine sodium excretion > 20 meq/L✓ Correct answer
- BHypernatremia and urine sodium excretion > 20meq/L
- CHyponatremia and hyperkalemia
- DHypernatremia and hypokalemia
Q9.A child with Tubercular meningitis (TBM) presents with hydrocephalus after VP shunt has polyuria and hyponatremia. The most probable diagnosis is:
- ACentral Diabetes insipidus
- BSIADH
- CCerebral salt wasting✓ Correct answer
- DShunt block
Answer key
Q1: A. Hypo-osmolar urine; Q2: B. Hyper secretion of ANP; Q3: A. Head trauma; Q4: A. Characterized by sudden increase in urine volume with decrease in urine osmolality independent of circulating vasopressin levels; Q5: C. SIADH; Q6: C. Mannitol; Q7: B. Vincristine; Q8: A. Hyponatremia and urine sodium excretion > 20 meq/L; Q9: C. Cerebral salt wasting.
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