Myeloproliferative Neoplasms and Aplastic Anaemia
- Previous year questions on Myeloproliferative Neoplasms and Aplastic Anaemia for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 29 live questions in Myeloproliferative Neoplasms and Aplastic Anaemia.
- 4 of 29 questions carry a verified exam year: 2017, 2018, 2019.
- Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following is NOT a myeloproliferative disease:
- APolycythemia rubra vera
- BAcute myeloid leukemia✓ Correct answer
- CChronic myeloid leukemia
- DEssential thrombocytosis
Q2.Which is not seen in polycythemia vera :
- AIncreased vitamin B12 binding capacity
- BIncrease erythropoietin level✓ Correct answer
- CIncrease RBC count
- DOcular congestion
Q3.The following statements about Fanconi's anaemia are true except
- AProgressive pancytopenia
- BIncreased predisposition to malignancy
- CAutosomal dominant inheritance✓ Correct answer
- DAssociated skeletal abnormalities involving thumb and radius
Q4.Exocrine pancreatic insufficiency, marrow failure with neutropenia is characteristic of:
- AFanconi anemia
- BDiamond Blackfan syndrome
- CShwachman - Diamond syndrome✓ Correct answer
- DDyskeratosis congenita
Q5.An asymptomatic patient on regular health checkup has platelet counts of 8,00,000/cu.mm. Next line of management is:
- AFollow up and observe✓ Correct answer
- BBone marrow biopsy
- CPlasmapheresis
- DPhlebotomy
Q6.Which of the following hematological problems may be precipitated by parvovirus?
- AHaemolytic crisis
- Baplastic crisis✓ Correct answer
- CPancytopenia
- DThrombocytopenia
Q7.Which is the most common preceding infection in bone marrow failure syndromes?
- AParvo B19
- BEBV
- CHIV
- DHepatitis✓ Correct answer
Q8.A 40 year male complaining of hot flushes each time he baths. Hb: 20%gm, Platelet: 89,000/mL, WBC: 30,000/mL, Investigation revealed JAK2 mutation. What is the most likely diagnosis?
- APMF
- BCML
- CPCV✓ Correct answer
- DEssential thrombocytosis
Q9.Gaisbock syndrome is better known as?
- APrimary familial polycythemia
- BHigh-altitude erythrocytosis
- CSpurious polycythemia✓ Correct answer
- DPolycythemia vera
Q10.A 45 year old female patient presents with symptoms of easy bruisability and frequent headaches. Physical examination show a moderate splenomegaly. Blood counts shows a normal leucocyte count and a platelet count of 1000 × 103/ cu mm. The leucocyte alkaline phosphatase score is normal. Which one of the following is the drug of choice for the treatment of this patient?a) Hydroxyureab) Radioactive phosphorusc) Anagrelided) Interferon alpha
- Acd✓ Correct answer
- Bbc
- Cbd
- Dac
Answer key
Q1: B. Acute myeloid leukemia; Q2: B. Increase erythropoietin level; Q3: C. Autosomal dominant inheritance; Q4: C. Shwachman - Diamond syndrome; Q5: A. Follow up and observe; Q6: B. aplastic crisis; Q7: D. Hepatitis; Q8: C. PCV; Q9: C. Spurious polycythemia; Q10: A. cd.
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