Vasculitis of Large and Medium Vessels

Previous year questions on Vasculitis of Large and Medium Vessels for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
24 live questions in Vasculitis of Large and Medium Vessels.
2 of 24 questions carry a verified exam year: 2017, 2019.
Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
Question set last updated 5 Sept 2026.

Q1.A 64 year old lady Kamla complains of severe unilateral headache on the right side and blindness for 2 days. On examination, there is a thick cord like structure on the lateral side of the head. The ESR is 80 mm/hr in the first hour. The most likely diagnosis is:
- ATemporal arteritis
- BMigraine
- CCluster headache
- DSinusitis
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Q2.A 65 year old lady underwent mastectomy for Carcinoma breast. Later she developed frontal headache, pain in temple region and around eye. Her ESR is 55 mm/hour. What is the most probable diagnosis?
- ACavernous sinus thrombosis
- BMeningeal metastasis
- CFrontal sinusitis
- DGiant cell arteritis
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Q3.A 30 years old male patient presents with complaints of weakness in right upper and both lower limbs of last 4 months. He developed digital infarcts involving 2nd and 3rd fingers on right side and 5th finger on left side. On examination, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. Investigations showed a Hb 12 gm, TLC -- 12000 Cu mm, Platelets 430,000; ESR -- 49 mm. Urine examination showed proteinuria and RBC -- 10-15/hpf with no casts. Which of the following is the most likely diagnosis?
- AWegener's granulomatosis
- BMixed cryoglobulemia
- CPolyarteritis nodosa
- DSLE
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Q4.Most specific symptom of temporal arteritis?
- AVisual loss
- BJaw claudication
- CTemporal headache
- DPolymyalgia rheumatica
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Q5.A 30 year old patient has right upper limb BP of 180/95 mm Hg and left upper limb BP of 130/90 mm Hg. He also has early diastolic murmur in right 2 intercostal space. Which of the following would be LEAST likely associated with these findings?
- ASupravalvular aortic Stenosis
- BCoarctation of aorta
- CTakayasu arteritis
- DAortic dissection
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Q6.A 55-year-old woman has had several weeks of fever, abdominal pain, weight loss, and lack of energy. Three days prior to the assessment, she developed a left foot drop. Her blood pressure is 160/90 mm Hg, pulse 80/min, and physical examination confirms left peroneal nerve damage and a bilateral sensory peripheral neuropathy in both legs. There are no skin rashes. Laboratory evaluation reveals ESR of 105 mm/h, WBC of 14,000/mL, and negative serologic tests for antineutrophil cytoplasmic antibody (ANCA) and ANA. The eosinophil count is normal, and urinalysis is negative for casts, protein, and red cells. Which of the following is the most likely mechanism for renal injury in this condition?
- Anephrotic syndrome
- Bdiffuse glomerulonephritis
- Cgranuloma formation
- Dnecrotizing vasculitis of vessels
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Q7.Which of the following is the most frequent presenting symptoms in patients with giant cell arteritis
- AHeadache
- BJaw claudication
- CPolymyalgia Rheumatica
- DBlindness
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Q8.In takayasu arteritis there is -
- AIntimal fibrosis
- BRenal hypertension
- CCoronary aneurysm
- DAll of the above
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Q9.All of the following statements are true regarding giant cell arteritis except:
- AMost commonly seen in old age patient ( more than 50 yrs)
- BClinical features include constitutional symptoms like fever, fatigue, weight loss, and pain along the course of temporal artery.
- C50% of the patient presents with ocular symptoms vary from diplopia to complete vision loss
- DIt usually involves the whole artery
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Q10.Which of the following is a feature of temporal arteritis
- AGiant cell arteritis
- BGranulomatous vasculitis
- CNecrotizing vasculitis
- DLeucocytoclastic vasculitis
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Answer key

Q1: A. Temporal arteritis; Q2: D. Giant cell arteritis; Q3: C. Polyarteritis nodosa; Q4: B. Jaw claudication; Q5: B. Coarctation of aorta; Q6: D. necrotizing vasculitis of vessels; Q7: A. Headache; Q8: D. All of the above; Q9: D. It usually involves the whole artery; Q10: B. Granulomatous vasculitis.

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Vasculitis of Large and Medium Vessels

Answer key

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