Haemoglobinopathies
- Previous year questions on Haemoglobinopathies for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 54 live questions in Haemoglobinopathies.
- 2 of 54 questions carry a verified exam year: 2019, 2020.
- Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which type of hemoglobin is not normally found within human erythrocytes?
- AHbA
- BHbA2
- CHbCO✓ Correct answer
- DHbO2
Q2.A boy after playing football complaining fatigue and abdominal pain. He also had a history of hand swelling in past. On ultrasonography, he has shrunken spleen. What is the likely diagnosis of this patient?
- ASickle cell anemia✓ Correct answer
- BIron deficiency anemia
- CAcute pancreatitis
- DIntermittent porphyria
Q3.NESTROFT test is a screening test for –
- Aβ–thalassemia✓ Correct answer
- BHereditary spherocytosis
- CAutoimmune hemolytic anemia
- DMegaloblastic anemia
Q4.Sickle cell mutation is
- APoint mutation✓ Correct answer
- BSelective mutation
- CFrame shift mutation
- DNonsense mutation
Q5.In alpha-thalassemia trait,electrophoresis shows:
- AIncreased HbF and normal HbA2
- BNormal HbF and normal HbA2✓ Correct answer
- CNormal HbF and decreased HbA2
- DDecreased HbF and normal HbA2
Q6.In alpha thalassemia
- AExcess alpha chain
- BNo alpha chain
- CExcess beta chain✓ Correct answer
- DNo beta chain
Q7.Sickle cell anemia is a -
- AGene deletion
- BGene modification
- CPoint mutation✓ Correct answer
- DFrame shift mutation
Q8.HbA2 is raised in:
- ABeta thalassemic trait✓ Correct answer
- BSickle cell anemia
- CHereditary spherocytosis
Q9."Hair-on-end" appearance in a skull roentgenogram is seen in :
- AFibrous dysplasia
- BThalassemia✓ Correct answer
- CGarre's Osteomyelitis
- DPagets disease
Q10.Mutation seen in sickle cell anemia:
- APoint✓ Correct answer
- BInsertion
- CDeletion
- DFrame shift
Answer key
Q1: C. HbCO; Q2: A. Sickle cell anemia; Q3: A. β–thalassemia; Q4: A. Point mutation; Q5: B. Normal HbF and normal HbA2; Q6: C. Excess beta chain; Q7: C. Point mutation; Q8: A. Beta thalassemic trait; Q9: B. Thalassemia; Q10: A. Point.
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