Macrocytic Anaemia
- Previous year questions on Macrocytic Anaemia for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Medicine section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 12 live questions in Macrocytic Anaemia.
- 2 of 12 questions carry a verified exam year: 2018, 2020.
- Medicine is worth about 33 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Vitamin B12 deficiency can lead to all EXCEPT:
- AMyopathy✓ Correct answer
- BPeripheral neuropathy
- COptic atrophy
- DMyelopathy
Q2.Which of the following statement about Schilling's test is false?
- AAbnormal in pernicious anemia
- BThe test is dependent on normal renal function.
- CAbnormal in ileal disease
- D58Co-labeled cobalamin is administered intramuscularly✓ Correct answer
Q3.In which clinical scenario, after giving folic acid, neuropathic features stas worsening?
- AVit B6 deficiency
- BVit B12 deficiency✓ Correct answer
- CVit B2 deficiency
- DVitamin C deficiency
Q4.A 30yr old patient complaints of easy fatigability exotional dyspnea and weight loss She also complaints of frequent fall There is B12 decrease in vibration sense Her Hb levels were low She was treated with folate Her anemia improved but neurological symptoms worsen d Which of the following is most probable reason of her condition
- AFolate not absorbed
- BDeficiency of folate reductase in CNS
- CUnmasked pyridoxine defficiency
- DFolate therapy caused rapid use of B12 stores aggravating symptoms✓ Correct answer
Q5.A 39-year-old man with chronic alcoholism is brought to the hospital after a fall, while intoxicated. He has completely recovered except for a bruise on his shoulder. His only abnormality is low hemoglobin of 9.6 g/dL, the platelets and WBC are normal. Additional tests including ferritin, vitamins B12, and folate are normal. Which of the following findings is most likely to be seen on his peripheral blood film?
- Amacrocytosis✓ Correct answer
- Bbasophilia
- Cred cell fragments
- Dincreased platelet adhesiveness
Q6.Megaloblastic anaemia due to folic acid deficiency is commonly due to -
- AInadequate dietary intake✓ Correct answer
- BDefective intestinal absorption
- CAbsence of folic acid binding protein in serum
- DAbsence of glutamic acid in the Intestine
Q7.1772. A patient presents with macroglossla and loss of tongue papilla. His Hb Is 11.5 and MCV Is 100. What shuld be the next step In investigating this patient ?
- AB12 estimation✓ Correct answer
- BBrush biopsy of the lesion
- CFluconazole treatment
- DIncision biopsy
Q8.Deficiency of the 'intrinsic factor of Castle' causes:
- AMicrocytic anemia
- BPernicious anemia✓ Correct answer
- CCooley's anemia
- DAplastic anemia
Q9.Megaloblastic anemia may be caused by all of the following except :
- APhenytoin
- BMethotrexate
- CPyrimethamine
- DAmoxycilline✓ Correct answer
Q10.Schilling test is done for ?
- AVitamin B12 deficiency✓ Correct answer
- BFolic acid deficiency
- CVitamin B6 deficiency
- DVitamin D deficiency
Answer key
Q1: A. Myopathy; Q2: D. 58Co-labeled cobalamin is administered intramuscularly; Q3: B. Vit B12 deficiency; Q4: D. Folate therapy caused rapid use of B12 stores aggravating symptoms; Q5: A. macrocytosis; Q6: A. Inadequate dietary intake; Q7: A. B12 estimation; Q8: B. Pernicious anemia; Q9: D. Amoxycilline; Q10: A. Vitamin B12 deficiency.
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