Cells and Organs of the Immune System
- Previous year questions on Cells and Organs of the Immune System for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 91 live questions in Cells and Organs of the Immune System.
- 4 of 91 questions carry a verified exam year: 2018, 2019.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.All of the following are categorized as secondary lymphoid organs except
- ALymph nodes
- BSpleen
- CThymus✓ Correct answer
- DSubepithelial collections of lymphocytes
Q2.Which portion of MHC1 complex forms the component of antigen presenting part?
- ABetween alpha 1 and beta 2 microglobulin
- BDistal part of alpha chain✓ Correct answer
- CProximal part of alpha chain
- DBetween alpha 2 and beta 2 microglobulin
Q3.Which is not true regarding superantigen
- ABind T cells irrespective of antigen specificity of TCR
- BBind directly to both MHC II and T cell receptor causing T cell activation
- CBind to cleft (antigen binding groove) in the MHC II molecule✓ Correct answer
- DBinds directly to lateral aspect of T cell receptor
Q4.a new agent was developed to increase the recognition of foreign antigens by antigen presenting cells .true regarding the physiological aspects of APCs
- Aantigen is presented MHC-1 complexes
- BAPCs are required before a response to viruses are generated
- Cdirect antibody stimulation still requires APCs
- Dantigen processed by APC are recognised by CD4+ T cells✓ Correct answer
Q5.The marker for B lymphocyte is -
- ACD 19✓ Correct answer
- BCD 68
- CCD 34
- DCD 4
Q6.Not a B cell marker
- ACD19
- BCD20
- CCD34✓ Correct answer
- DCD10
Q7.IL-2 is produced by:
- AT cells✓ Correct answer
- BB cells
- CMonocytes
- DNeutrophils
Q8.IL -1 produces -
- AT lymphocyte activation✓ Correct answer
- BDelayed wound healing
- CIncreased pain perception
- DDecreased PMN release from bone marrow
Q9.True statements are all except:
- AChromosome six has the genes for MHC
- BGenes encoding complement proteins are located adjacent to class I
- CMonocytes have MHC II antigens on their surface
- DClass III does not encode complement✓ Correct answer
Q10.Memory T cell can be identified using the following marker
- ACD45RA
- BCD45RB
- CCD45RC
- DCD45RO✓ Correct answer
Answer key
Q1: C. Thymus; Q2: B. Distal part of alpha chain; Q3: C. Bind to cleft (antigen binding groove) in the MHC II molecule; Q4: D. antigen processed by APC are recognised by CD4+ T cells; Q5: A. CD 19; Q6: C. CD34; Q7: A. T cells; Q8: A. T lymphocyte activation; Q9: D. Class III does not encode complement; Q10: D. CD45RO.
Other topics in Pathology
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- Necrosis and Apoptosis
- Intracellular Accumulations, Pathological Calcification and Cell Ageing
- The Acute Inflammatory Response
- Chemical Mediators and Granulomatous Inflammation
- Wound Healing and Tissue Repair
- Hemodynamic and Hemostatic Disorders
- Patterns of Inheritance
- Lysosomal and Glycogen Storage Disorders
- Chromosomal and Other Genetic Disorders
- Features and Epidemiology of Neoplasia
- Molecular Basis of Cancer and Tumour Immunity
- Carcinogenesis, Paraneoplastic Syndromes and Tumour Markers
- Hypersensitivity Reactions and Autoimmune Disease
- Immunodeficiency Disorders
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- Histopathology Techniques and Special Stains
- Microcytic Anemias
- Normocytic and Macrocytic Anemias
- Hemolysis Overview and Intravascular Hemolysis
- Extravascular Hemolytic Anemias
- G6PD Deficiency and Autoimmune Hemolysis
- Disorders of Platelets
- Disorders of the Coagulation Cascade
- Blood Components and Transfusion Reactions
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Hodgkin Lymphoma
- Non-Hodgkin Lymphoma: Overview
- Non-Hodgkin Lymphoma: Low Grade
- Non-Hodgkin Lymphoma: High Grade
- Multiple Myeloma and Other Plasma Cell Neoplasms
- Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis
- White Cell Disorders and Lymphadenitis
- Atherosclerosis and Hypertensive Vascular Disease
- Aneurysms and Arterial Dissection
- Vasculitis
- Vascular Tumours
- Heart Failure and Ischemic Heart Disease
- Cardiomyopathies, Pericardial Disease and Cardiac Tumours
- Valvular and Congenital Heart Disease
- Rheumatic Fever and Endocardial Disease
- Diseases of the Glomerulus
- Tubulointerstitial, Vascular and Cystic Renal Disease
- Renal Tumours
- Pathology of the Lower Urinary Tract
- Pathology of the Female Genital Tract
- Pathology of the Male Genital Tract
- Infectious and Alcohol-Related Liver Disease
- Metabolic and Autoimmune Liver Disease
- Tumours of the Liver and Biliary Tract
- Gallbladder and Pancreatic Disease
- Esophageal Pathology
- Gastric Pathology
- Small Bowel Pathology
- Large Bowel: Non-Neoplastic Disease
- Large Bowel: Neoplastic Disease
- Congenital Anomalies, ARDS and Lung Infections
- Obstructive and Restrictive Lung Disease
- Lung Tumours
- Pituitary, Parathyroid and Endocrine Pancreas
- Thyroid Gland Pathology
- Adrenal Gland Pathology
- Breast Pathology
- Bone: Developmental Disorders, Infections and Tumours
- Joint and Soft Tissue Pathology
- Dermatopathology
- CNS Infections and Cerebrovascular Disease
- Degenerative, Toxic and Metabolic CNS Disease
- Tumours of the CNS
- Peripheral Nerve and Neuromuscular Pathology