Necrosis and Apoptosis
- Previous year questions on Necrosis and Apoptosis for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 57 live questions in Necrosis and Apoptosis.
- 6 of 57 questions carry a verified exam year: 2017, 2018, 2019, 2020.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Liquefactive necrosis is seen in:
- AHeart
- BBrain✓ Correct answer
- CLungs
- DSpleen
Q2.In apoptosis, Apaf-1 is activated by release of which of the following substance from the mitochondria?
- ABcl-2
- BBax
- CBcl-XL
- DCytochrome C✓ Correct answer
Q3.CD 95 has a major role in
- AApoptosis✓ Correct answer
- BCell necrosis
- CInterferon activation
- DProteolysis
Q4.Which of the following type of necrosis is seen in blood vessel due to immune complex mediated damage?
- ACoagulative necrosis
- BLiquefactive necrosis
- CFibrinoid necrosis✓ Correct answer
- DCaseous necrosis
Q5.Which is activated for nuclear fragmentation in apoptosis?
- ACaspases✓ Correct answer
- BApaf-1
- COxygen free radicals
Q6.Coagulative necrosis is seen in -
- ATuberculosis✓ Correct answer
- BFungal infection
- CSarcoidosis
- DWet gangrene
Q7.DNA NICK AND LABELLING (insitu) technique is used to see?
- Aamount of total DNA in a mitochondria
- Bfraction of nucleic acids
- Cfraction of cells in apoptotic pathway quantified✓ Correct answer
- Dfraction of cells in meotic division is quantified
Q8.The following are examples of apoptosis, except
- AMenstrual cycle
- BTumour necrosis✓ Correct answer
- CGraft versus host disease
- DPathological atrophy following duct obstruction
Q9.Ladder pattern of DNA electrophoresis in apoptosis is caused by the action of following enzyme
- AEndonuclease✓ Correct answer
- BTransglutaminase
- CDNAse
- DCaspase
Q10.All the following are signs of necrosis Except
- ALipofuscin✓ Correct answer
- BCell Membrane Rupture
- CKaryolysis
- DKaryorrhexis
Answer key
Q1: B. Brain; Q2: D. Cytochrome C; Q3: A. Apoptosis; Q4: C. Fibrinoid necrosis; Q5: A. Caspases; Q6: A. Tuberculosis; Q7: C. fraction of cells in apoptotic pathway quantified; Q8: B. Tumour necrosis; Q9: A. Endonuclease; Q10: A. Lipofuscin.
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