Large Bowel: Neoplastic Disease
- Previous year questions on Large Bowel: Neoplastic Disease for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 18 live questions in Large Bowel: Neoplastic Disease.
- 1 of 18 questions carries a verified exam year: 2017.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following colonic polyps is not premalignant?
- AJuvenile polyps✓ Correct answer
- BHamartomatous polyps associated with Peutz Jeghers Syndrome
- CVillous adenomas
- DTubular adenomas
Q2.Strong correlation with colorectal cancer is seen in
- APeutz-Jegher's polyp
- BFamilial polyposis coli✓ Correct answer
- CJuvenile polyposis
- DHyperplastic polyp
Q3.All of the following genes are implicated in colon carcinoma by classical pathway except
- AAPC
- BK-ras
- CBeta-catenin
- DMismatch repair genes✓ Correct answer
Q4.False about familial polyposis colon cancer syndrome:
- AAutosomal recessive transmission✓ Correct answer
- BAssociated with fibroma and osteomas
- CAssociated with brain tumors
- D100% chance of colon carcinomas
Q5.Gardner syndrome does not include:
- AOsteomas
- BEpidermoid cysts
- COsteosarcoma✓ Correct answer
- DImpacted permanent teeth
Q6.Mucocutaneous circumoral pigmentation is found in:
- APeutz-Jeghers syndrome✓ Correct answer
- BPlummer-Vinson syndrome
- CLead poisoning
- DBechet's syndrome
Q7.True about familial adenomatous polyposis is?
- AAlso known as Lynch syndrome
- BFAP gene is located on 5p21
- C100% risk of malignancy in classical variety✓ Correct answer
- DMales are usual carriers
Q8.On rectal examination, a patient is found to have a large, fungating mass protruding into the rectal lumen. Biopsy of this mass demonstrates an invasive malignant tumor composed of glandular structures. The development of this condition is most strongly associated with
- ADiverticulitis
- BDiverticulosis
- CJuvenile polyposis syndrome
- DUlcerative colitis✓ Correct answer
Q9.Colonic polyp that has maximum chance of malignant transformation
- AHyperplastic polyp
- BAdenomatous polyp✓ Correct answer
- CJuvenile polyp
- DPolyp of Peutz-Jeghers syndrome
Q10.The adenomatous polyp of large bowel are most often situated in -
- AAscending colon
- BTransverse colon
- CDescending colon
- DSigmoid colon✓ Correct answer
Answer key
Q1: A. Juvenile polyps; Q2: B. Familial polyposis coli; Q3: D. Mismatch repair genes; Q4: A. Autosomal recessive transmission; Q5: C. Osteosarcoma; Q6: A. Peutz-Jeghers syndrome; Q7: C. 100% risk of malignancy in classical variety; Q8: D. Ulcerative colitis; Q9: B. Adenomatous polyp; Q10: D. Sigmoid colon.
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