Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis
- Previous year questions on Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 40 live questions in Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis.
- 2 of 40 questions carry a verified exam year: 2017, 2018.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Punctuated lesion and floating teeth are seen in
- AMetastasis
- BOsteitis fibrosa
- CHistiocytosis✓ Correct answer
- DAsbestosis
Q2.False statement regarding Myelodysplasia
- APatient with 5q deletion have poor prognosis✓ Correct answer
- BErythroid cells with basophilic stippling are seen
- CMicromegakaryocytes are seen in bone marrow
- DHypolobulated neutrophils are seen in peripheral blood
Q3.Following are seen in polycythemia vera except:
- AMost common cause of polycythemia
- BIncreased erythropoietin✓ Correct answer
- CErythropoietin independent growth of red cell progenitors
- DIntrinsic abnormality of hematopoietic precursors
Q4.Immunohistochemistry marker of histiocytosis X
- ACD1a✓ Correct answer
- BCD57
- CCD3
- DCD68
Q5.&;Birbeck granules&; are seen in
- AHistiocytosis X✓ Correct answer
- BGaucher's Disease
- CAlbinism
- DAll of the above
Q6.BCR-ABL1 gene fusion is seen in all of the following Except
- AAcute myeloid leukemia
- BChronic myeloid leukemia
- CAcute lymphoblastic leukemia
- DChronic lymphocytic leukemia✓ Correct answer
Q7.Massive splenomegaly is least likely to occur in
- ACML
- BPrimary thrombocytosis✓ Correct answer
- CPCV
- DPrimary myelofibrosis
Q8.Which of the following is the most common clinical manifestation of Rosai Dorfman disease?
- ATender, red plaques and nodules together with areas of erythema
- BPainless cervical lymphadenopathy✓ Correct answer
- CNoncicatricial alopecia
- DRecurrent staphylococcal skin infections.
Q9.in a case of plycythemia vera which of the following rceptor overactivity is seen?
- Atyrosine kinase
- Bjak 2✓ Correct answer
- Cc GMP
- Dnone of the above
Q10.Dinesh, a 24-year-old male, complains of loose teeth in a single quadrant. His radiograph shows irregular bone loss and histopathology reveals eosinophils and histiocytes. The most probable diagnosis is:
- AHand-Schuller-Christian disease✓ Correct answer
- BPaget's disease
- COsteoclastoma
- DAlbright's syndrome
Answer key
Q1: C. Histiocytosis; Q2: A. Patient with 5q deletion have poor prognosis; Q3: B. Increased erythropoietin; Q4: A. CD1a; Q5: A. Histiocytosis X; Q6: D. Chronic lymphocytic leukemia; Q7: B. Primary thrombocytosis; Q8: B. Painless cervical lymphadenopathy; Q9: B. jak 2; Q10: A. Hand-Schuller-Christian disease.
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