Hypersensitivity Reactions and Autoimmune Disease
- Previous year questions on Hypersensitivity Reactions and Autoimmune Disease for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 33 live questions in Hypersensitivity Reactions and Autoimmune Disease.
- 1 of 33 questions carries a verified exam year: 2018.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Ram Devi presented with generalized edema sweating and flushing tachycardia and fever after bee sting. This is :
- AT cell mediated cytotoxicity
- BIgE mediated reaction✓ Correct answer
- CIgG mediated reaction
- DIgA mediated hypersensitivity reaction
Q2.Patch test is what type of hypersensitivity reaction?
- AType I
- BType II
- CType III
- DType IV✓ Correct answer
Q3.Lack of reaction to our own HLA ( human leukocyte antigen ) is known as?
- AAutoimmunity
- BClonal selection
- CTolerance✓ Correct answer
- DComplement system
Q4.All of the following autoimmune disorder are more common in females except
- AITP
- BMultiple sclerosis
- CType I diabetes✓ Correct answer
- DScleroderma
Q5.Which of the following is not an autoimmune disorder?
- AUlcerative colitis✓ Correct answer
- BGrave's disease
- CRheumatoid arthritis
- DSLE
Q6.Anaphylaxis is mediated by
- A5-hydroxytryptamine
- BHeparin
- CProstaglandin
- DAll of these✓ Correct answer
Q7.A type of immediately occurring reaction in which antigens combine with antibodies already attached to the surface of mast cells and basophils is called:
- AType I hypersensitivity✓ Correct answer
- BType II hypersensitivity
- CType III hypersensitivity
- DType IV hypersensitivity
Q8.Which of the following cannot be diagnosed without positive ANA?
- ADrug induced lupus
- BSLE✓ Correct answer
- CSjogren syndrome
- DScleroderma
Q9.Serum sickness syndrome is:
- AA transplant immunity
- BAn anaphylactic shock
- CSystemic arthus reaction✓ Correct answer
- DNone of the above
Q10.In penicillin allergy, penicillin acts as a:
- AHapten✓ Correct answer
- BCarrier
- CSuper antigen
- DToxin
Answer key
Q1: B. IgE mediated reaction; Q2: D. Type IV; Q3: C. Tolerance; Q4: C. Type I diabetes; Q5: A. Ulcerative colitis; Q6: D. All of these; Q7: A. Type I hypersensitivity; Q8: B. SLE; Q9: C. Systemic arthus reaction; Q10: A. Hapten.
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