Diseases of the Glomerulus

• Q1.Non-proliferative Glomerulonephritis include all of the following, except:

  • AFocal Segmental Glomerulonephritis (FSGS)
  • BMesangiocapillary Glomerulonephritis
  • CMembranous Glomerulonephritis
  • DAmyloidosis
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• Q2.Renal vein thrombosis is most commonly associated with :

  • ADiabetic nephropathy
  • BMembranous glomerulopathy
  • CMinimal change disease
  • DMesangio-proliferative glomerulonephritis
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• Q3.About Fibronectin nephropathy, which of the following is false?

  • AAutosomal recessive
  • BCharacterized by mesangial deposits
  • CDoes not have antibody or complement deposition
  • DIs characterized by endothelial Ig deposits
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• Q4.Which of the following is associated with pauci-immune glomerulonephritis?

  • ASLE nephritis
  • BAnti-GBM glomerulonephritis
  • CIgA nephropathy
  • DGranulomatosis with polyangiitis (GPA)
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• Q5.A 7 year old boy presented with generalized edema. Urine examination revealed marked albuminuria. Serum biochemical examinations showed hypoalbuminemia with hyperlipidemia. Kidney biopsy was undertaken. On light microscopic examination, the kidney appeared normal. Electron microscopic examination is most likely to reveal:

  • AFusion of foot processes of the glomerular epithelial cells
  • BRarefaction of glomerular basement membrane
  • CDeposition of electron dense material in the basement membrane
  • DThin basement membrane
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• Q6.MC cause of nephrotic syndrome in adults:-

  • AGood-pasture syndrome
  • BMembranous GN
  • CMinimal change disease
  • DFocal segmental glomerulosclerosis
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• Q7.Which among the following is characteristic of a/c glomerulonephritis:

  • AMuddy brown Cast
  • BFeNa < 1%
  • CHaematuria Proteinuria
  • DWBC
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• Q8.Which of these is a Nephritic syndrome?

  • AMinimal change disease
  • BMembranous Glomerulopathy
  • CPost infectious Glomerulonephritis
  • DFocal segmental glomerulosclerosis
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• Q9.Loss of foot processes seen on electron microscopy of renal biopsy is a classical feature in which of the following?

  • AMembranous nephropathy
  • BMinimal change disease
  • CIgA nephropathy
  • DRapidly progressive glomerulonephritis
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• Q10.Disease which may present with proteinuria:-

  • AArteritis
  • BPolycystic kidney disease
  • CPyelonephritis
  • DGlomerulonephritis
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Answer key

Q1: B. Mesangiocapillary Glomerulonephritis; Q2: B. Membranous glomerulopathy; Q3: A. Autosomal recessive; Q4: D. Granulomatosis with polyangiitis (GPA); Q5: A. Fusion of foot processes of the glomerular epithelial cells; Q6: D. Focal segmental glomerulosclerosis; Q7: C. Haematuria Proteinuria; Q8: C. Post infectious Glomerulonephritis; Q9: B. Minimal change disease; Q10: D. Glomerulonephritis.

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