Disorders of the Coagulation Cascade
- Previous year questions on Disorders of the Coagulation Cascade for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 36 live questions in Disorders of the Coagulation Cascade.
- 4 of 36 questions carry a verified exam year: 2017, 2018, 2019.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Disseminated intravascular coagulation ( DIC) differs from thrombotic thrombocytopenic purpura. In this reference the DIC is most likely characterized by -
- ASignificant numbers of schistocytes
- BA brisk reticulocytosis
- CDecreased coagulation factor levels✓ Correct answer
- DSignificant thrombocytopenia
Q2.Which of the following is not true regarding Von Willebrand disease?
- ANormal platelet count
- BQuantitative defects are seen in subtypes 1 and 3 von Willebrand disease
- CHemarthrosis is the usual presentation✓ Correct answer
- DProduced by endothelial cells
Q3.Classical hemophilia is due to the absence of
- ASmall part of factor VIII✓ Correct answer
- BLarge part of factor VIII
- CSmall part of factor IX
- DLarge part of factor IX
Q4.Pseudotumor syndrome is seen in
- ASLE
- BThalassemia
- CHemophilia✓ Correct answer
- DHyperparathyroidism
Q5.A patient with post-partum hemorrhage had about 2 liters of blood loss. Investigation revealed normal PT and a prolonged aPTT. Test to differentiate between coagulation factor deficiency and factor inhibitor is:
- ATissue thromboplastin inhibition time
- BEcarin clotting time
- CDilute Russel viper venom time
- DMixing studies✓ Correct answer
Q6.Best test that shows the integrity of intrinsic pathway of clotting mechanism
- Ableeding time
- BaPTT✓ Correct answer
- Cprothrombin time
- Dclotting time
Q7.The following test may be abnormal in disseminated intravascular coagulation except:
- AProthrombin
- BActivated partial thromboplastin time
- CD-dimer levels
- DClot solubility.✓ Correct answer
Q8.Patient with increased PT, APTT & TT and normal fibrinogen and platelet counts, diagnosis is?
- ADIC
- BFac. VIII def.
- CLiver disease✓ Correct answer
- DVitamin K deficiency
Q9.Which among the following laboratory investigation is best to reveal bleeding in Disseminated Intravascular Coagulation (DIC)?
- AIncreased PT
- BIncreased aPTT
- CDecreased fibrinogen
- DIncreased FDPs✓ Correct answer
Q10.A boy complains of bleeding gums, swollen, Joints with hemorrhage into joints. His paternal and maternal uncle complains of same problem. It is due to deficiency of factor:
- AVIII✓ Correct answer
- BIX
- CX
- DVI
Answer key
Q1: C. Decreased coagulation factor levels; Q2: C. Hemarthrosis is the usual presentation; Q3: A. Small part of factor VIII; Q4: C. Hemophilia; Q5: D. Mixing studies; Q6: B. aPTT; Q7: D. Clot solubility; Q8: C. Liver disease; Q9: D. Increased FDPs; Q10: A. VIII.
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