Hemolysis Overview and Intravascular Hemolysis
- Previous year questions on Hemolysis Overview and Intravascular Hemolysis for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 21 live questions in Hemolysis Overview and Intravascular Hemolysis.
- 5 of 21 questions carry a verified exam year: 2017, 2018, 2019.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following is a cause of intravascular hemolysis
- ACold agglutinin disease
- BWarm type autoimmune hemolytic anaemia
- CPNH✓ Correct answer
- DBoth bc
Q2.Mutation of which of the following gene is most important in paroxysmal nocturnal hemoglobinuria?
- ADecay accelerating factor (DAF)
- BMembrane inhibitor of reactive lysis (MIRL)
- CGlycosyl phosphatidyl inositol (GPI)✓ Correct answer
- DCD8 binding protein
Q3.Schistocytes in peripheral smear are seen in all except:
- ADIC
- BSickle cell anemia✓ Correct answer
- CTTP
- DHUS
Q4.Hemolysis is predominantly intravascular in which of the following conditions?
- AWarm-type autoimmune hemolytic anemia
- BPNH✓ Correct answer
- CCold-type autoimmune hemolytic anemia
- DHereditary spherocytosis
Q5.An abnormal Ham test is most likely associated with which of the following ?
- ADefect in spectrin
- BDefective GPI anchor✓ Correct answer
- CDefect in complement
- DMannose-binding residue defect
Q6.Secondary hemolytic anemia is seen in all except:
- ACML✓ Correct answer
- BCLL
- CContinuous renal replacement therapy (CRRT)
- DExtra corporeal membrane oxygenation (ECMO)
Q7.t1/2 of haptoglobin complex is:
- A5 days
- B3 days
- C10 days
- D10 minutes✓ Correct answer
Q8.Helmet cells are characteristic of anemia of
- AHemolytic uremic syndrome✓ Correct answer
- BPolysplenia
- CSpherocytosis
- DAcanthocytosis
Q9.PNH patients will be having deficient surface proteins that normally protect the red cells from activated compliments. What are the two deficient surface proteins?
- ACD 45 and CD 59
- BCD 51 and CD 59
- CCD 55 and CD 59✓ Correct answer
- DCD58 and CD 59
Q10.The differential diagnosis of micro-angiopathic anemia includes all Except:
- ASepsis
- BHemolytic uremic syndrome
- CMI✓ Correct answer
- DEclampsia
Answer key
Q1: C. PNH; Q2: C. Glycosyl phosphatidyl inositol (GPI); Q3: B. Sickle cell anemia; Q4: B. PNH; Q5: B. Defective GPI anchor; Q6: A. CML; Q7: D. 10 minutes; Q8: A. Hemolytic uremic syndrome; Q9: C. CD 55 and CD 59; Q10: C. MI.
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