Non-Hodgkin Lymphoma: High Grade
- Previous year questions on Non-Hodgkin Lymphoma: High Grade for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 17 live questions in Non-Hodgkin Lymphoma: High Grade.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.t(2,8) is characteristically seen with
- APreB cell lymphoma
- BPreT cell lymphoma
- CBurkitt's lymphoma✓ Correct answer
- DMantle cell lymphoma
Q2.The t (8;14) translocation is associated with activation of which of the following genes?
- Ac-abl
- Bc-myc✓ Correct answer
- Cbcl-2
- Dbcl-1
Q3.Hallmark cells are seen in
- ADiffuse large B cell lymphoma
- BHodgkin lymphoma
- CAnaplastic large cell lymphoma✓ Correct answer
- DHairy cell leukemia
Q4.Which of the following is anaplastic lymphoma kinase (ALK) positive neoplasm?
- ASynovial sarcoma
- BFibromatosis
- CEwing sarcoma
- DInflammatory myofibroblastic tumor✓ Correct answer
Q5.A 10-year old boy was presented with a mass in abdomen. On imaging, the para-aortic lymph nodes were enlarged. On biopsy, starry sky appearance was seen. What is the underlying abnormality?
- Ap53 gene mutation
- BRb gene mutation
- CTranslocation involving BCR-ABL gene
- DTranslocation involving Myc gene✓ Correct answer
Q6.A man living in southern Japan contracts HTLV-1 infection through sexual contact. Twenty-five years later he develops generalized lymphadenopathy with hepatosplenomegaly, a skin rash,hypercalcemia, and an elevated white blood count. This man has most likely developed which of the following?
- AAIDS
- BAutoimmunity
- CDelayed hypersensitivity reaction
- DLeukemia✓ Correct answer
Q7.Burkitt's lymphoma is - a) B cell lymphoma b) 6, 14 translocation c) Can present as abdominal mass d) Radiotherapy is used in treatment
- Aa
- Bbc
- Cac✓ Correct answer
- Db
Q8.All of the following statements about Burkitt's lymphoma are true, Except:
- AB cell lymphoma
- B8, 14 translocation
- CCan present as an abdominal mass
- DRadiotherapy is the treatment of choice✓ Correct answer
Q9.Oncogene associated with burkitt's lymphoma is:
- ABCL-1, IgH
- BBCL-2, IgH
- CC-MYC✓ Correct answer
- DALK
Q10.About Burkitt's lymphoma-What is true -
- ACD34+ve & surface Immuno Globulin +ve
- BCD34+ve & surface Immuno Globulin -ve
- CCD34-ve & surface Immuno Globulin -ve
- DCD34-ve & surface Immuno Globulin +ve✓ Correct answer
Answer key
Q1: C. Burkitt's lymphoma; Q2: B. c-myc; Q3: C. Anaplastic large cell lymphoma; Q4: D. Inflammatory myofibroblastic tumor; Q5: D. Translocation involving Myc gene; Q6: D. Leukemia; Q7: C. ac; Q8: D. Radiotherapy is the treatment of choice; Q9: C. C-MYC; Q10: D. CD34-ve & surface Immuno Globulin +ve.
Other topics in Pathology
- Cell Genetics, Adaptation and Cell Injury
- Necrosis and Apoptosis
- Intracellular Accumulations, Pathological Calcification and Cell Ageing
- The Acute Inflammatory Response
- Chemical Mediators and Granulomatous Inflammation
- Wound Healing and Tissue Repair
- Hemodynamic and Hemostatic Disorders
- Patterns of Inheritance
- Lysosomal and Glycogen Storage Disorders
- Chromosomal and Other Genetic Disorders
- Features and Epidemiology of Neoplasia
- Molecular Basis of Cancer and Tumour Immunity
- Carcinogenesis, Paraneoplastic Syndromes and Tumour Markers
- Cells and Organs of the Immune System
- Hypersensitivity Reactions and Autoimmune Disease
- Immunodeficiency Disorders
- Amyloidosis and Transplant Rejection
- Histopathology Techniques and Special Stains
- Microcytic Anemias
- Normocytic and Macrocytic Anemias
- Hemolysis Overview and Intravascular Hemolysis
- Extravascular Hemolytic Anemias
- G6PD Deficiency and Autoimmune Hemolysis
- Disorders of Platelets
- Disorders of the Coagulation Cascade
- Blood Components and Transfusion Reactions
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Hodgkin Lymphoma
- Non-Hodgkin Lymphoma: Overview
- Non-Hodgkin Lymphoma: Low Grade
- Multiple Myeloma and Other Plasma Cell Neoplasms
- Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis
- White Cell Disorders and Lymphadenitis
- Atherosclerosis and Hypertensive Vascular Disease
- Aneurysms and Arterial Dissection
- Vasculitis
- Vascular Tumours
- Heart Failure and Ischemic Heart Disease
- Cardiomyopathies, Pericardial Disease and Cardiac Tumours
- Valvular and Congenital Heart Disease
- Rheumatic Fever and Endocardial Disease
- Diseases of the Glomerulus
- Tubulointerstitial, Vascular and Cystic Renal Disease
- Renal Tumours
- Pathology of the Lower Urinary Tract
- Pathology of the Female Genital Tract
- Pathology of the Male Genital Tract
- Infectious and Alcohol-Related Liver Disease
- Metabolic and Autoimmune Liver Disease
- Tumours of the Liver and Biliary Tract
- Gallbladder and Pancreatic Disease
- Esophageal Pathology
- Gastric Pathology
- Small Bowel Pathology
- Large Bowel: Non-Neoplastic Disease
- Large Bowel: Neoplastic Disease
- Congenital Anomalies, ARDS and Lung Infections
- Obstructive and Restrictive Lung Disease
- Lung Tumours
- Pituitary, Parathyroid and Endocrine Pancreas
- Thyroid Gland Pathology
- Adrenal Gland Pathology
- Breast Pathology
- Bone: Developmental Disorders, Infections and Tumours
- Joint and Soft Tissue Pathology
- Dermatopathology
- CNS Infections and Cerebrovascular Disease
- Degenerative, Toxic and Metabolic CNS Disease
- Tumours of the CNS
- Peripheral Nerve and Neuromuscular Pathology