Intracellular Accumulations, Pathological Calcification and Cell Ageing
- Previous year questions on Intracellular Accumulations, Pathological Calcification and Cell Ageing for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 28 live questions in Intracellular Accumulations, Pathological Calcification and Cell Ageing.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Which of the following is not compatible with ageing?
- ADecrease cross linkage✓ Correct answer
- BDecrease superoxide dismutase
- CIncrease accumulation free radicals
- DAccumulated mutations in somatic cell
Q2.Dystrophic calcification is seen in
- AMilk alkali syndrome
- BAtheromatous plaque✓ Correct answer
- CHyperparathyroidism
- DVitamin A intoxication
Q3.which of the following is the etiology of werner syndrome with premature aging
- Aincreased length of telomere
- Bsho telomere with damaged DNA and loss of helicase✓ Correct answer
- CIncreased advanced glycation and products
- DDecreased lipid peroxidation
Q4.which of the following is not a theory of mechanism of AGING ?
- Afree radicle theory
- Bcrosslinking the collagen theory
- Ctelomerase shortening theroy
- Dlysosomal degeneration theory✓ Correct answer
Q5.Metastatic calcification is most commonly seen in
- ACornea
- BExtensor tendon
- CLungs
- DRenal tubules✓ Correct answer
Q6.True about metastatic calcification
- ASerum Ca level is normal
- BOccurs in dead/dying tissue
- COccurs in damaged heart valves
- DCalcification stas in mitochondria✓ Correct answer
Q7.All of the following are associated with increased ageing, except
- AEnlargement of telomere✓ Correct answer
- BDecrease in number of mitochondria
- CGlycosylation of DNA
- DGlycosylation of RNA
Q8.Russell's bodies are found in:
- AActivated macrophages
- BHistiocytes
- CPlasma cells✓ Correct answer
- DErythrocytes
Q9.Example of Dystrophic calcification-
- AHyperparathyroidism
- BSarcoidosis
- CHypervitaminosis D
- DMyositis ossificans✓ Correct answer
Q10.Lipofuscin containing macrophages are a feature of?
- AWear and tear✓ Correct answer
- BFat deposit
- CIron deficiency
- DCalcification
Answer key
Q1: A. Decrease cross linkage; Q2: B. Atheromatous plaque; Q3: B. sho telomere with damaged DNA and loss of helicase; Q4: D. lysosomal degeneration theory; Q5: D. Renal tubules; Q6: D. Calcification stas in mitochondria; Q7: A. Enlargement of telomere; Q8: C. Plasma cells; Q9: D. Myositis ossificans; Q10: A. Wear and tear.
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