Chemical Mediators and Granulomatous Inflammation
- Previous year questions on Chemical Mediators and Granulomatous Inflammation for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 96 live questions in Chemical Mediators and Granulomatous Inflammation.
- 6 of 96 questions carry a verified exam year: 2018, 2019.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Both antibody dependent and independent complement pathway converge on which complement component-
- AC3✓ Correct answer
- BC5
- CC4
- DC8
Q2.Which of the following molecules activates "Classically activated macrophage"/M1 type macrophage?
- AIFN-g✓ Correct answer
- BIL-4
- CIL-13
- DIL-1
Q3.Chemotaxis is mediated by?
- AC5a✓ Correct answer
- BIL-2
- CIFN-g
- DIL-5
Q4.Which of the following best denotes classical complement pathway activation in immune inflammatory condition?
- AC2, C4 and C3 decreased✓ Correct answer
- BC2 and C4 normal, C3 is decreased
- CC3 normal and C2, C4 decreased
- DC2, C4, C3 all are elevated
Q5.which of the following is hallmak of CHRONIC INFLAMMATION ?
- Atissue destruction
- Bmononuclear infiltration
- Cwound healing and repair
- Dall of the above✓ Correct answer
Q6.Preformed mediator of inflammation is
- ASerotonin✓ Correct answer
- BProstaglandin
- CDopamine
- DLeukotrienes
Q7.Interleukin responsible for pyrexia is?
- AIL1✓ Correct answer
- BIL6
- CINF gamma
- DIFN alpha
Q8.Caspase involved in activation of IL_1 is which of the following?
- ACaspase 1✓ Correct answer
- BCaspase 3
- CCaspase 5
- DCaspase 8
Q9.Earliest feature of TB:-
- AGranuloma
- BLangerhan's Giant cells
- CLymphocytosis✓ Correct answer
- DCaseation
Q10.Mediators of inflammation are all except -
- ATNF
- BIFN
- CMyeloperoxidase✓ Correct answer
- DProstaglandins/Interleukins
Answer key
Q1: A. C3; Q2: A. IFN-g; Q3: A. C5a; Q4: A. C2, C4 and C3 decreased; Q5: D. all of the above; Q6: A. Serotonin; Q7: A. IL1; Q8: A. Caspase 1; Q9: C. Lymphocytosis; Q10: C. Myeloperoxidase.
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- Intracellular Accumulations, Pathological Calcification and Cell Ageing
- The Acute Inflammatory Response
- Wound Healing and Tissue Repair
- Hemodynamic and Hemostatic Disorders
- Patterns of Inheritance
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- Hemolysis Overview and Intravascular Hemolysis
- Extravascular Hemolytic Anemias
- G6PD Deficiency and Autoimmune Hemolysis
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- Blood Components and Transfusion Reactions
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- Hodgkin Lymphoma
- Non-Hodgkin Lymphoma: Overview
- Non-Hodgkin Lymphoma: Low Grade
- Non-Hodgkin Lymphoma: High Grade
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- Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis
- White Cell Disorders and Lymphadenitis
- Atherosclerosis and Hypertensive Vascular Disease
- Aneurysms and Arterial Dissection
- Vasculitis
- Vascular Tumours
- Heart Failure and Ischemic Heart Disease
- Cardiomyopathies, Pericardial Disease and Cardiac Tumours
- Valvular and Congenital Heart Disease
- Rheumatic Fever and Endocardial Disease
- Diseases of the Glomerulus
- Tubulointerstitial, Vascular and Cystic Renal Disease
- Renal Tumours
- Pathology of the Lower Urinary Tract
- Pathology of the Female Genital Tract
- Pathology of the Male Genital Tract
- Infectious and Alcohol-Related Liver Disease
- Metabolic and Autoimmune Liver Disease
- Tumours of the Liver and Biliary Tract
- Gallbladder and Pancreatic Disease
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- Large Bowel: Neoplastic Disease
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- Bone: Developmental Disorders, Infections and Tumours
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