Immunodeficiency Disorders
- Previous year questions on Immunodeficiency Disorders for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 37 live questions in Immunodeficiency Disorders.
- 4 of 37 questions carry a verified exam year: 2017, 2018, 2019.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Humoral immunodeficiency is suspected in a patient and he is under investigation. Which of the following infections would not be consistent with the diagnosis?
- AGiardiasis
- BPneumocystis carinii pneumonia✓ Correct answer
- CRecurrent sinusitis
- DRecurrent subcutaneous abscesses
Q2.N. meningitidis can be due to deficiency of this complement system:
- AC1-C4 deficiency
- BC5-C9 deficiency✓ Correct answer
- CC3 deficiency
- DC2 deficiency
Q3.Which of the following is true about ataxia telangiectasia?
- AIt is associated with normal immune function
- BSerum levels of IgA are increased
- CIt is an autosomal recessive disease✓ Correct answer
- DThere is absence of amphicytes in different organs
Q4.All are true about Wiskott-Aldrich syndrome except :
- ABloody diarrhea during infancy
- BLow IgM and elevated IgA and IgE
- CLarge size platelets✓ Correct answer
- DAtopic dermatitis
Q5.Ataxia telangiectasia is associated with all of the following except
- ARecurrent sinopulmonary infections
- BLymphatic reticular malignancies
- CIncreased fraction of IgA immunoglobulins✓ Correct answer
- DInsulin resistance
Q6.6 yr old child presented to OPD with eczematous rash On evaluation was found to have fever platelests 80,000 on enquiry multiple hospitalisation for recurrent infections
- ABruton's agammaglobulinemia
- Bchediak Higashi syndrome
- CWiscott Aldrich syndrome✓ Correct answer
- DSevere combined immunodeficiency
Q7.All are true regarding Hyper IgE syndrome except-
- AInheritance is as a single locus Autosomal dominant trait with variable expression
- BCoarse facial features
- CRecurrent staphylococcal abscesses involving skin, lungs
- DHigh serum IgE with low IgG, IgA and IgM✓ Correct answer
Q8.Adenosine deaminase deficiency is seen in the following:
- ACommon variable immunodeficiency
- BSevere combined immunodeficiency✓ Correct answer
- CChronic granulomatous disease
- DNezelof syndrome
Q9.Nezelof&;s syndrome is recurrent episodes of:
- AAppendicitis
- BCholecystitis
- CIntestinal obstruction
- DPneumonia✓ Correct answer
Q10.Recurrent Neisseria infections are associated with deficiency of
- AC5
- BC6
- CC7
- DAll of above✓ Correct answer
Answer key
Q1: B. Pneumocystis carinii pneumonia; Q2: B. C5-C9 deficiency; Q3: C. It is an autosomal recessive disease; Q4: C. Large size platelets; Q5: C. Increased fraction of IgA immunoglobulins; Q6: C. Wiscott Aldrich syndrome; Q7: D. High serum IgE with low IgG, IgA and IgM; Q8: B. Severe combined immunodeficiency; Q9: D. Pneumonia; Q10: D. All of above.
Other topics in Pathology
- Cell Genetics, Adaptation and Cell Injury
- Necrosis and Apoptosis
- Intracellular Accumulations, Pathological Calcification and Cell Ageing
- The Acute Inflammatory Response
- Chemical Mediators and Granulomatous Inflammation
- Wound Healing and Tissue Repair
- Hemodynamic and Hemostatic Disorders
- Patterns of Inheritance
- Lysosomal and Glycogen Storage Disorders
- Chromosomal and Other Genetic Disorders
- Features and Epidemiology of Neoplasia
- Molecular Basis of Cancer and Tumour Immunity
- Carcinogenesis, Paraneoplastic Syndromes and Tumour Markers
- Cells and Organs of the Immune System
- Hypersensitivity Reactions and Autoimmune Disease
- Amyloidosis and Transplant Rejection
- Histopathology Techniques and Special Stains
- Microcytic Anemias
- Normocytic and Macrocytic Anemias
- Hemolysis Overview and Intravascular Hemolysis
- Extravascular Hemolytic Anemias
- G6PD Deficiency and Autoimmune Hemolysis
- Disorders of Platelets
- Disorders of the Coagulation Cascade
- Blood Components and Transfusion Reactions
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Hodgkin Lymphoma
- Non-Hodgkin Lymphoma: Overview
- Non-Hodgkin Lymphoma: Low Grade
- Non-Hodgkin Lymphoma: High Grade
- Multiple Myeloma and Other Plasma Cell Neoplasms
- Myelodysplastic and Myeloproliferative Neoplasms and Histiocytosis
- White Cell Disorders and Lymphadenitis
- Atherosclerosis and Hypertensive Vascular Disease
- Aneurysms and Arterial Dissection
- Vasculitis
- Vascular Tumours
- Heart Failure and Ischemic Heart Disease
- Cardiomyopathies, Pericardial Disease and Cardiac Tumours
- Valvular and Congenital Heart Disease
- Rheumatic Fever and Endocardial Disease
- Diseases of the Glomerulus
- Tubulointerstitial, Vascular and Cystic Renal Disease
- Renal Tumours
- Pathology of the Lower Urinary Tract
- Pathology of the Female Genital Tract
- Pathology of the Male Genital Tract
- Infectious and Alcohol-Related Liver Disease
- Metabolic and Autoimmune Liver Disease
- Tumours of the Liver and Biliary Tract
- Gallbladder and Pancreatic Disease
- Esophageal Pathology
- Gastric Pathology
- Small Bowel Pathology
- Large Bowel: Non-Neoplastic Disease
- Large Bowel: Neoplastic Disease
- Congenital Anomalies, ARDS and Lung Infections
- Obstructive and Restrictive Lung Disease
- Lung Tumours
- Pituitary, Parathyroid and Endocrine Pancreas
- Thyroid Gland Pathology
- Adrenal Gland Pathology
- Breast Pathology
- Bone: Developmental Disorders, Infections and Tumours
- Joint and Soft Tissue Pathology
- Dermatopathology
- CNS Infections and Cerebrovascular Disease
- Degenerative, Toxic and Metabolic CNS Disease
- Tumours of the CNS
- Peripheral Nerve and Neuromuscular Pathology