Multiple Myeloma and Other Plasma Cell Neoplasms
- Previous year questions on Multiple Myeloma and Other Plasma Cell Neoplasms for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 22 live questions in Multiple Myeloma and Other Plasma Cell Neoplasms.
- 4 of 22 questions carry a verified exam year: 2018, 2019.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Regarding multiple myeloma which of the following statements is wrong:
- AMalignant neoplasm derived from plasma cells
- BMultiple punched out lesions on radiograms of the skull
- CMultiple hot spots on bone scan✓ Correct answer
- DMelphalan is used in treatment.
Q2.Palatal edema is significant for:-
- AAlpha heavy chain disease
- BGamma heavy chain disease✓ Correct answer
- CMu heavy chain disease
- DBeta heavy chain disease
Q3.Waldenstrom's macroglobulinemia is seen in
- ANHL
- BPlasmocytic Lymphoma✓ Correct answer
- CCLL
Q4.Myeloma associated with good prognosis:
- At(11:14)✓ Correct answer
- Bdeletion of 13q
- Cdel 17p
- Dt(14,16)
Q5."Raindrop skull" is seen in
- AHemophilia
- BThalassemia
- CMultiple Myeloma✓ Correct answer
- DHodgkin's lymphoma
Q6.Which among the following statements is wrong
- ALight chains are synthesised in slight excess normally in plasma cells
- BQualitative assessment of M component can be done by electrophoresis
- CM components are detected in chronic myeloid leukaemia✓ Correct answer
- DIn 20% myelomas, only light chains are produced
Q7.All of the following are poor prognostic markers of multiple myeloma, except:
- At(11;14)✓ Correct answer
- Bt(14;16)
- C1q gain
- Dt(14;20)
Q8.All are poor prognostic for multiple myeloma except
- At (11 14)✓ Correct answer
- Bt (14 16)
- C1q gain
- Dt (4 14)
Q9.Multiple punched out lesions are seen in:
- APaget's disease
- BOsteosarcoma
- CEwing sarcoma
- DMultiple myeloma✓ Correct answer
Q10.Multiple punched out lesions in soft skull are seen in
- AMultiple myeloma✓ Correct answer
- BSecondaries
- CMalignancy
- DMedulloblastoma
Answer key
Q1: C. Multiple hot spots on bone scan; Q2: B. Gamma heavy chain disease; Q3: B. Plasmocytic Lymphoma; Q4: A. t(11:14); Q5: C. Multiple Myeloma; Q6: C. M components are detected in chronic myeloid leukaemia; Q7: A. t(11;14); Q8: A. t (11 14); Q9: D. Multiple myeloma; Q10: A. Multiple myeloma.
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