Pathology of the Male Genital Tract
- Previous year questions on Pathology of the Male Genital Tract for NEET PG (National Eligibility cum Entrance Test - Postgraduate), from the Pathology section of the exam.
- Most questions here come from previous-year papers of Indian postgraduate medical entrance and licensing exams; where a paper and year are recorded the question carries them. The image-based questions are original vignettes written around an openly licensed figure, and were never asked in any exam.
- 13 live questions in Pathology of the Male Genital Tract.
- Pathology is worth about 25 of 300 questions on the exam. See every subject’s weightage.
- Question set last updated 6 Sept 2026.
Q1.Induration of seminal vesicle is seen most often in
- ATuberculosis✓ Correct answer
- BGonorrhea
- CSyphilis
- DLymphogranuloma venereum
Q2.A baby is born with a testicular mass. Histologic sections made of the homogeneous yellow white mass after its removal demonstrate epithelial-lined spaces that have flattened-to-cuboidal epithelial cells with vacuolated cytoplasm containing eosinophilic, hyaline-like globules. Scattered structures resembling primitive glomeruli (endodermal sinuses) are also seen. If appropriate immunohistochemical stains are performed, the eosinophilic cytoplasmic globules would most likely contain which of the following?
- AAlpha-fetoprotein✓ Correct answer
- BEstrogen receptors
- CHuman chorionic gonadotropin
- DHuman papilloma virus
Q3.A 23-year-old, sexually active man has been treated for Neisseria gonorrhoeae infection 6 times during the past 5 years. He now comes to the physician because of the increasing number and size of warty lesions slowly enlarging on his external genitalia during the past year. On physical examination, there are multiple 1- to 3-mm sessile, nonulcerated, papillary excrescences over the inner surface of the penile prepuce. These lesions are excised, but 2 years later, similar lesions appear. Which of the following conditions most likely predisposed him to the development of these recurrent lesions?
- ACandida albicans infection
- BCircumcision
- CHuman papillomavirus infection✓ Correct answer
- DNeisseria gonorrhoeae infection
Q4.A 58-year-old man presents to the emergency department with severe back pain. His history is negative for trauma and he has no other complaints. He denies urinary frequency, hesitancy, or dysuria. A digital rectal examination confirms the presence of a firm, hard, asymmetrical and stony prostate, suggestive of prostatic malignancy. In addition to PSA, which of the following markers can be demonstrated in the tumour cells?
- AAMACR✓ Correct answer
- BAFP
- CPodoplanin
- DOCT-3/4
Q5.All the following are testicular dysgenesis syndromes except:
- ACryptorchidism
- BEpispadias✓ Correct answer
- CPoor sperm quality
- DHypospadias
Q6.Commonest histological type of carcinoma testis is:
- ATeratoma
- BYolk sac tumour
- CSeminoma✓ Correct answer
- DChoriocarcinoma
Q7.Predisposing features for germ cell tumour - a) Cryptorchidism b) Testicular feminising syndrome c) Klinefelter's syndrome d) Smoking e) Right side more common than Left side
- Abcde
- Babcd
- Cabce✓ Correct answer
- Dabde
Q8.Reinke crystalloids can be seen in which of the following sex cord-stromal tumours?
- ALeydig cell tumour✓ Correct answer
- BGranulosa cell tumour
- CGonadoblastoma
- DThecoma
Q9.All are true about seminomas except:
- AMost common type of germ cell tumor
- BAnaplastic seminomas is associated with a worse prognosis✓ Correct answer
- CAlmost never occur in infants
- DSpermatocytic seminoma is slow growing with good prognosis
Q10.A 25 year old man undergoes orchiectomy for a testicular tumor. Microscopically, the tumor shows a variety of patterns, including lobules containing large cells with watery cytoplasm, structures resembling primitive glomeruli, syncytiotrophoblast, and shafts of undifferentiated cells with focal glandular differentiation. Which of the following terms most accurately describes this tumor?
- AChoriocarcinoma
- BEmbryonal carcinoma
- CMixed tumor✓ Correct answer
- DSeminoma
Answer key
Q1: A. Tuberculosis; Q2: A. Alpha-fetoprotein; Q3: C. Human papillomavirus infection; Q4: A. AMACR; Q5: B. Epispadias; Q6: C. Seminoma; Q7: C. abce; Q8: A. Leydig cell tumour; Q9: B. Anaplastic seminomas is associated with a worse prognosis; Q10: C. Mixed tumor.
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